The value of hypersensitivity quantitative fecal immunochemical test in early colorectal cancer detection

At present, both the incidence and mortality rates of colorectal cancer are on the rise, making early screening a crucial tool in reducing the fatality rate. Although colonoscopy is the recommended method according to the guidelines, compliance tends to be poor. The fecal immunochemical test (FIT),...

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Bibliographic Details
Published in:Postgraduate medical journal 2024-02, Vol.100 (1181), p.135-141
Main Authors: Jiang, Lianghong, Xu, Fen, Feng, Weiwei, Fu, Chen, Zhou, Changjiang
Format: Article
Language:English
Subjects:
Colonoscopy
Colorectal Neoplasms - diagnosis
Early Detection of Cancer - methods
Feces
Humans
Mass Screening - methods
Occult Blood
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Summary:At present, both the incidence and mortality rates of colorectal cancer are on the rise, making early screening a crucial tool in reducing the fatality rate. Although colonoscopy is the recommended method according to the guidelines, compliance tends to be poor. The fecal immunochemical test (FIT), a new technology that uses latex immunoturbidimetry to detect fecal blood, offers high specificity and sensitivity. Additionally, it is low-cost, easy to operate, and less likely to be affected by food and drugs, thus improving the compliance rate for population screening. Compared to other screening techniques, FIT represents a safer and more accurate option. This article reviews the application of FIT in early colorectal cancer screening.
ISSN:0032-5473
1469-0756
DOI:10.1093/postmj/qgad114