Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia

Objective Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH). Study design This is a retrospective cohort study of infants with C...

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Bibliographic Details
Published in:Journal of perinatology 2024-03, Vol.44 (3), p.354-359
Main Authors: Hari Gopal, Srirupa, Martinek, Kelly F., Holmes, Amanda, Hagan, Joseph L., Fernandes, Caraciolo J.
Format: Article
Language:English
Subjects:
692/308/409
692/699/1785
Blood Gas Analysis
Congenital diseases
Correlation coefficient
Correlation coefficients
Death
Diaphragm
Diaphragm (Anatomy)
Extracorporeal Membrane Oxygenation
Hernia
Hernias, Diaphragmatic, Congenital - therapy
Humans
Infant
Infant, Newborn
Infants
Medicine
Medicine & Public Health
Mortality
Neonatal care
Newborn babies
Oxygen
Oxygen content
Oxygen Saturation
Oxygenation
Pediatric Surgery
Pediatrics
Regression analysis
Retrospective Studies
Saturation index
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Summary:Objective Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH). Study design This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death. Results Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876, p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-023-01845-8