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Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia
Objective Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH). Study design This is a retrospective cohort study of infants with C...
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| Published in: | Journal of perinatology 2024-03, Vol.44 (3), p.354-359 |
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| container_issue | 3 |
| container_start_page | 354 |
| container_title | Journal of perinatology |
| container_volume | 44 |
| creator | Hari Gopal, Srirupa Martinek, Kelly F. Holmes, Amanda Hagan, Joseph L. Fernandes, Caraciolo J. |
| description | Objective
Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
Study design
This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
Results
Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876,
p
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| doi_str_mv | 10.1038/s41372-023-01845-8 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2902961403</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2941495400</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-a34b540648b6f1b5e56253e62bf1d67b6f09639df4deb49d26b8988f391d91fb3</originalsourceid><addsrcrecordid>eNp9kMlOwzAQhi0EomV5AQ7IEhcuAW9xbG6oYpMq9QI3JMuJnTZV4hQ7kdq3x23KIg5cbGnmm39GHwAXGN1gRMVtYJhmJEGEJggLlibiAIwxy3iSpowegjHKGE0EZXwETkJYIrRtZsdgRAXKMGF4DN5n683cOhh013vdVa2DlTN2fQe1g9ose1d0sGw9bHfcLyK-sGhdLFadrqGp9Grh9byJSAEX1rtKn4GjUtfBnu__U_D2-PA6eU6ms6eXyf00KWiWdommLE8Z4kzkvMR5alNOUmo5yUtseBaLSHIqTcmMzZk0hOdCClFSiY3EZU5PwfWQu_LtR29Dp5oqFLautbNtHxSRiEiOGaIRvfqDLtveu3hdpBhmMh6CIkUGqvBtCN6WauWrRvuNwkht3avBvYru1c69EnHoch_d54013yNfsiNAByDEVhTnf3b_E_sJsYOPNg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2941495400</pqid></control><display><type>article</type><title>Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia</title><source>Nexis UK</source><source>Springer Nature</source><creator>Hari Gopal, Srirupa ; Martinek, Kelly F. ; Holmes, Amanda ; Hagan, Joseph L. ; Fernandes, Caraciolo J.</creator><creatorcontrib>Hari Gopal, Srirupa ; Martinek, Kelly F. ; Holmes, Amanda ; Hagan, Joseph L. ; Fernandes, Caraciolo J.</creatorcontrib><description>Objective
Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
Study design
This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
Results
Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876,
p
< 0.001). The linear regression equation was OI = −2.4 + 2.4(OSI).
Conclusion
OSI could be used as a valuable adjunct to OI in the clinical management of newborn infants with CDH.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-023-01845-8</identifier><identifier>PMID: 38071241</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/308/409 ; 692/699/1785 ; Blood Gas Analysis ; Congenital diseases ; Correlation coefficient ; Correlation coefficients ; Death ; Diaphragm ; Diaphragm (Anatomy) ; Extracorporeal Membrane Oxygenation ; Hernia ; Hernias, Diaphragmatic, Congenital - therapy ; Humans ; Infant ; Infant, Newborn ; Infants ; Medicine ; Medicine & Public Health ; Mortality ; Neonatal care ; Newborn babies ; Oxygen ; Oxygen content ; Oxygen Saturation ; Oxygenation ; Pediatric Surgery ; Pediatrics ; Regression analysis ; Retrospective Studies ; Saturation index</subject><ispartof>Journal of perinatology, 2024-03, Vol.44 (3), p.354-359</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer Nature America, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a34b540648b6f1b5e56253e62bf1d67b6f09639df4deb49d26b8988f391d91fb3</citedby><cites>FETCH-LOGICAL-c375t-a34b540648b6f1b5e56253e62bf1d67b6f09639df4deb49d26b8988f391d91fb3</cites><orcidid>0000-0001-6934-3253 ; 0000-0001-5744-3409 ; 0000-0002-4027-5805</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38071241$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hari Gopal, Srirupa</creatorcontrib><creatorcontrib>Martinek, Kelly F.</creatorcontrib><creatorcontrib>Holmes, Amanda</creatorcontrib><creatorcontrib>Hagan, Joseph L.</creatorcontrib><creatorcontrib>Fernandes, Caraciolo J.</creatorcontrib><title>Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><addtitle>J Perinatol</addtitle><description>Objective
Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
Study design
This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
Results
Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876,
p
< 0.001). The linear regression equation was OI = −2.4 + 2.4(OSI).
Conclusion
OSI could be used as a valuable adjunct to OI in the clinical management of newborn infants with CDH.</description><subject>692/308/409</subject><subject>692/699/1785</subject><subject>Blood Gas Analysis</subject><subject>Congenital diseases</subject><subject>Correlation coefficient</subject><subject>Correlation coefficients</subject><subject>Death</subject><subject>Diaphragm</subject><subject>Diaphragm (Anatomy)</subject><subject>Extracorporeal Membrane Oxygenation</subject><subject>Hernia</subject><subject>Hernias, Diaphragmatic, Congenital - therapy</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infants</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mortality</subject><subject>Neonatal care</subject><subject>Newborn babies</subject><subject>Oxygen</subject><subject>Oxygen content</subject><subject>Oxygen Saturation</subject><subject>Oxygenation</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Regression analysis</subject><subject>Retrospective Studies</subject><subject>Saturation index</subject><issn>0743-8346</issn><issn>1476-5543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kMlOwzAQhi0EomV5AQ7IEhcuAW9xbG6oYpMq9QI3JMuJnTZV4hQ7kdq3x23KIg5cbGnmm39GHwAXGN1gRMVtYJhmJEGEJggLlibiAIwxy3iSpowegjHKGE0EZXwETkJYIrRtZsdgRAXKMGF4DN5n683cOhh013vdVa2DlTN2fQe1g9ose1d0sGw9bHfcLyK-sGhdLFadrqGp9Grh9byJSAEX1rtKn4GjUtfBnu__U_D2-PA6eU6ms6eXyf00KWiWdommLE8Z4kzkvMR5alNOUmo5yUtseBaLSHIqTcmMzZk0hOdCClFSiY3EZU5PwfWQu_LtR29Dp5oqFLautbNtHxSRiEiOGaIRvfqDLtveu3hdpBhmMh6CIkUGqvBtCN6WauWrRvuNwkht3avBvYru1c69EnHoch_d54013yNfsiNAByDEVhTnf3b_E_sJsYOPNg</recordid><startdate>20240301</startdate><enddate>20240301</enddate><creator>Hari Gopal, Srirupa</creator><creator>Martinek, Kelly F.</creator><creator>Holmes, Amanda</creator><creator>Hagan, Joseph L.</creator><creator>Fernandes, Caraciolo J.</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7T5</scope><scope>7T7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6934-3253</orcidid><orcidid>https://orcid.org/0000-0001-5744-3409</orcidid><orcidid>https://orcid.org/0000-0002-4027-5805</orcidid></search><sort><creationdate>20240301</creationdate><title>Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia</title><author>Hari Gopal, Srirupa ; Martinek, Kelly F. ; Holmes, Amanda ; Hagan, Joseph L. ; Fernandes, Caraciolo J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a34b540648b6f1b5e56253e62bf1d67b6f09639df4deb49d26b8988f391d91fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>692/308/409</topic><topic>692/699/1785</topic><topic>Blood Gas Analysis</topic><topic>Congenital diseases</topic><topic>Correlation coefficient</topic><topic>Correlation coefficients</topic><topic>Death</topic><topic>Diaphragm</topic><topic>Diaphragm (Anatomy)</topic><topic>Extracorporeal Membrane Oxygenation</topic><topic>Hernia</topic><topic>Hernias, Diaphragmatic, Congenital - therapy</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infants</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mortality</topic><topic>Neonatal care</topic><topic>Newborn babies</topic><topic>Oxygen</topic><topic>Oxygen content</topic><topic>Oxygen Saturation</topic><topic>Oxygenation</topic><topic>Pediatric Surgery</topic><topic>Pediatrics</topic><topic>Regression analysis</topic><topic>Retrospective Studies</topic><topic>Saturation index</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hari Gopal, Srirupa</creatorcontrib><creatorcontrib>Martinek, Kelly F.</creatorcontrib><creatorcontrib>Holmes, Amanda</creatorcontrib><creatorcontrib>Hagan, Joseph L.</creatorcontrib><creatorcontrib>Fernandes, Caraciolo J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hari Gopal, Srirupa</au><au>Martinek, Kelly F.</au><au>Holmes, Amanda</au><au>Hagan, Joseph L.</au><au>Fernandes, Caraciolo J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia</atitle><jtitle>Journal of perinatology</jtitle><stitle>J Perinatol</stitle><addtitle>J Perinatol</addtitle><date>2024-03-01</date><risdate>2024</risdate><volume>44</volume><issue>3</issue><spage>354</spage><epage>359</epage><pages>354-359</pages><issn>0743-8346</issn><eissn>1476-5543</eissn><abstract>Objective
Our objective was to investigate the correlation of Oxygen Saturation Index (OSI) with Oxygenation Index (OI) and determine OSImax values that could predict need for ECMO and death in Congenital Diaphragmatic Hernia (CDH).
Study design
This is a retrospective cohort study of infants with CDH admitted to a tertiary level VI NICU. Pearson’s correlation coefficient and simple linear regression analysis were used to investigate the OSI: OI correlation, and logistic regression analysis to investigate OSImax values that predicted need for ECMO and death.
Results
Among the 180 infants, OSImax value of >13 at 6 h of life (HOL) best predicted need for ECMO and death. There was a strong correlation between OSI: OI paired values (r = 0.876,
p
< 0.001). The linear regression equation was OI = −2.4 + 2.4(OSI).
Conclusion
OSI could be used as a valuable adjunct to OI in the clinical management of newborn infants with CDH.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>38071241</pmid><doi>10.1038/s41372-023-01845-8</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-6934-3253</orcidid><orcidid>https://orcid.org/0000-0001-5744-3409</orcidid><orcidid>https://orcid.org/0000-0002-4027-5805</orcidid></addata></record> |
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| ispartof | Journal of perinatology, 2024-03, Vol.44 (3), p.354-359 |
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| source | Nexis UK; Springer Nature |
| subjects | 692/308/409 692/699/1785 Blood Gas Analysis Congenital diseases Correlation coefficient Correlation coefficients Death Diaphragm Diaphragm (Anatomy) Extracorporeal Membrane Oxygenation Hernia Hernias, Diaphragmatic, Congenital - therapy Humans Infant Infant, Newborn Infants Medicine Medicine & Public Health Mortality Neonatal care Newborn babies Oxygen Oxygen content Oxygen Saturation Oxygenation Pediatric Surgery Pediatrics Regression analysis Retrospective Studies Saturation index |
| title | Oxygen saturation index: an adjunct for oxygenation index in congenital diaphragmatic hernia |
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