Anemia in liver transplant recipients: prevalence, severity, risk factors, and survival

Information about anemia in liver transplant (LTx) recipients is scarce. We investigated the prevalence and severity of anemia before and within the first-year post-LTx, risk factors for having anemia before LTx, and 1-year survival according to anemia status before LTx. This retrospective cohort st...

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Bibliographic Details
Published in:APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2024-03, Vol.132 (3), p.152-160
Main Authors: Hegland, Nina Øksnes, Rezahosseini, Omid, Pedersen, Christian Ross, Møller, Dina Leth, Bugge, Terese Brun, Wareham, Neval Ete, Arentoft, Nicoline Stender, Hillingsø, Jens, Lund, Thomas Kromann, Rasmussen, Allan, Nielsen, Susanne Dam
Format: Article
Language:English
Subjects:
Anemia
Liver
Liver diseases
Liver transplantation
Liver transplants
Males
Risk factors
Statistical analysis
Survival
Transplantation
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Summary:Information about anemia in liver transplant (LTx) recipients is scarce. We investigated the prevalence and severity of anemia before and within the first-year post-LTx, risk factors for having anemia before LTx, and 1-year survival according to anemia status before LTx. This retrospective cohort study received data from The Knowledge Center for Transplantation database at Rigshospitalet, Copenhagen, Denmark. Uni- and multivariate logistic regression were used to investigate factors associated with anemia and a Kaplan-Meier plot to illustrate the probability of survival. We included 346 first-time adult LTx recipients. The median age was 50 years (IQR: 42-57), and 203 (59%) were male. The prevalence of anemia before and 1-year post-LTx were 69 and 45%, respectively. Male sex (aOR 4.0 [95% CI: 2.2-7.2]; p 
ISSN:0903-4641
1600-0463
DOI:10.1111/apm.13364