The Use of MR-Guided Radiation Therapy for Pancreatic Cancer

The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for...

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Bibliographic Details
Published in:Seminars in radiation oncology 2024-01, Vol.34 (1), p.23-35
Main Authors: Daamen, Lois A, Parikh, Parag J, Hall, William A
Format: Article
Language:English
Subjects:
Humans
Magnetic Resonance Imaging - methods
Magnetic Resonance Spectroscopy
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - radiotherapy
Prospective Studies
Quality of Life
Radiosurgery - methods
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Summary:The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.
ISSN:1053-4296
1532-9461
DOI:10.1016/j.semradonc.2023.10.002