Autonomic Responses During Acute Anterior Versus Inferior Myocardial Infarction: A Systematic Review and Meta-Analysis

Autonomic responses elicited by myocardial infarction vary depending on the site of injury, but accurate assessment using heart rate variability during the acute phase is limited. We systematically searched PubMed without language restrictions throughout July 2023. We reviewed studies reporting auto...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-11, Vol.15 (11), p.e48893-e48893
Main Authors: Schismenos, Vaios, Tzanis, Alexander A, Papadopoulos, Georgios E, Nikas, Dimitrios, Koniari, Ioanna, Kolettis, Theofilos M
Format: Article
Language:English
Subjects:
Age
Blood pressure
Heart attacks
Heart rate
Ischemia
Medical prognosis
Meta-analysis
Mortality
Nervous system
Observational studies
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Summary:Autonomic responses elicited by myocardial infarction vary depending on the site of injury, but accurate assessment using heart rate variability during the acute phase is limited. We systematically searched PubMed without language restrictions throughout July 2023. We reviewed studies reporting autonomic indices separately for anterior and inferior infarcts, followed by a meta-analysis of those reporting the standard deviation of the inter-beat interval between normal sinus beats during the initial 24 hours after the onset of symptoms. Six studies were included, comprising 341 patients (165 anterior, 176 inferior infarcts), all with satisfactory scores on the Newcastle-Ottawa quality scale. The estimated average of the standardized mean difference (based on the random-effects model) was -0.722 (95% confidence intervals: -0.943 to -0.501), which differed from zero (z=-6.416, p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.48893