Neuroimaging correlation with EEG in status epilepticus

• Published in: Seizure (London, England) England), 2024-01, Vol.114, p.106-110
• Main Authors: Lee, Dong Ah, Sohn, GyeongMo, Park, Kang Min, Kim, Sung Eun
• Format: Article
• Language: English
• Subjects: Electroencephalography - methods; Humans; Neuroimaging; Retrospective Studies; Seizures; Status Epilepticus - diagnostic imaging
• ISSN: 1059-1311; 1532-2688
• DOI: 10.1016/j.seizure.2023.12.007

This study was to correlate EEG patterns with peri‑ictal perfusion CT abnormality (PCA) or peri‑ictal MR abnormality (PMA) in patients with status epilepticus (SE). This is a retrospective study done with SE patients from January 2016 to December 2021. We defined the PCA as single or multi-territorial cortical and/or thalamic hyper-perfusion. The PMA was defined as increased signal intensity in multiple brain regions including the cortex and subcortical regions. EEG patterns were categorized into electrographic seizure (ESz)/electroclinical seizure (ECSz), ictal-interictal continuum (IIC), and lateralized periodic discharges (LPDs) per the American Clinical Neurophysiology Society's guideline. We analyzed the association between the patterns of EEG and the presence of PCA or PMA. Among 73 patients, 26 % (19/73) showed PCA and 25 % (18/73) demonstrated PMA. The patterns of EEG were as follows; ESz/ECSz in 25 % (18/73), IIC in 34 % (25/73), and LPD in 12 % (9/73). There was a significant correlation between the patterns of EEG and the presence of PMA, but not PCA. 48 % (12/25) had both PMA and PCA whereas 52 % (13/25) showed either PMA (6/25) or PCA (7/25). Although PCA did not reveal an electro-radiographical correlation, PMA was strongly linked to ESz, ECSz, IIC, and LPD.