Analysis of the efficacy of blunt separation combined with uncrosslinked sodium hyaluronate composite solution for the treatment of tear trough deformity in Asians

Background Filling therapy is becoming increasingly popular for correcting tear trough deformities (TTD). However, its therapeutic effect and retention time are limited. Aims To improve the clinical efficacy and safety of TTD treatment in Asians, we used a blunt separation technique to break the adh...

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Bibliographic Details
Published in:Journal of cosmetic dermatology 2024-04, Vol.23 (4), p.1259-1268
Main Authors: Dong, Richeng, Jin, Qingmei, Zhi, Jiahui, Jin, Meilin, Gao, Yang, Nan, Meilan, Jin, Zhehu, Jin, Chenglong
Format: Article
Language:English
Subjects:
Aging
blunt separation
Collagen
Informed consent
Medical technology
Metabolism
Patient satisfaction
Skin
Sodium
sodium hyaluronate composite solution injection
Statistical analysis
Surgery
tear trough deformity
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Summary:Background Filling therapy is becoming increasingly popular for correcting tear trough deformities (TTD). However, its therapeutic effect and retention time are limited. Aims To improve the clinical efficacy and safety of TTD treatment in Asians, we used a blunt separation technique to break the adhesion site of periorbital subcutaneous tissue, and while repairing skin dermis after injury, it was combined with uncrosslinked hyaluronic acid compound solution to promote collagen regeneration and treat TTDs. Patients/Methods Twenty‐six Chinese patients (21 women and 5 men) with TTD, with a mean age of 34.54 ± 9.21 (range, 20–56) years, were enrolled. Symptom improvement, recurrence rates, treatment safety, and patient satisfaction were evaluated. Results All patients' tear trough rating scale (TTRS) scores decreased significantly immediately after treatment. The TTRS scores at 1, 3, and 6 months, and 1 year after treatment demonstrated significant differences from those before treatment (all p 
ISSN:1473-2130
1473-2165
DOI:10.1111/jocd.16151