Neurophysiological pain education for patients with symptomatic knee osteoarthritis: A systematic review and meta-analysis

• Published in: Patient education and counseling 2024-03, Vol.120, p.108128-108128, Article 108128
• Main Authors: Lesmond, Inès, Calvache-Mateo, Andrés, Heredia-Ciuró, Alejandro, Martín-Núñez, Javier, Navas-Otero, Alba, López-López, Laura, Valenza, Marie Carmen
• Format: Article
• Language: English
• ISSN: 0738-3991; 1873-5134
• DOI: 10.1016/j.pec.2023.108128

To evaluate the effectiveness of neurophysiological pain education in patients with symptomatic knee osteoarthritis considering pain-related variables. A systematic review and meta-analysis was carried out according to the PRISMA guidelines. A search was conducted in PubMed, PEDro Database, Cochrane Library, Scopus, and Web of Science. Only randomized controlled trials enrolling patients ≥ 18 years of age with symptomatic knee osteoarthritis were included. The Downs and Black quality assessment tool was used to assess the quality of the articles, and the risk of bias was evaluated with the Cochrane Risk of Bias Assessment Tool. A total of 7 studies were included in the study. Most of the studies were rated as "fair" on the Downs and Black quality assessment tool, and in the category of "some concerns" according to the Cochrane Risk of Bias Assessment Tool. Neurophysiological pain education was conducted alone or combined with exercise, joint mobilizations, or self-management programs. The number of sessions ranged from 1 to 10. The meta-analysis results showed significant differences in favor of the intervention group in pain (MD = -0.49; 95% CI = -0.66; -0.32; p