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A nomogram to predict the risk of cognitive impairment in patients with depressive disorder
This study was to describe the cognitive function status in patients with depressive disorder and to construct a nomogram model to predict the risk factors of cognitive impairment in these patients. From October 2019 to February 2021, a total of 141 patients with depressive disorder completed the su...
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Published in: | Research in nursing & health 2024-06, Vol.47 (3), p.302-311 |
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creator | Jian, Ya‐Ling Jia, Shoumei Shi, Shenxun Shi, Zhongying Zhao, Ying |
description | This study was to describe the cognitive function status in patients with depressive disorder and to construct a nomogram model to predict the risk factors of cognitive impairment in these patients. From October 2019 to February 2021, a total of 141 patients with depressive disorder completed the survey in two hospitals. The Montreal cognitive assessment (MoCA) was used with a cutoff score of 26 to differentiate cognitive impairment. Univariable and multivariable logistic regression analyses were conducted to identify independent risk factors. A nomogram was then constructed based on the results of the multivariable logistic regression analysis. The patients had an average MoCA score of 23.99 ± 3.02. The multivariable logistic regression analysis revealed that age (OR: 1.096, 95% CI: 1.042–1.153, p |
doi_str_mv | 10.1002/nur.22364 |
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From October 2019 to February 2021, a total of 141 patients with depressive disorder completed the survey in two hospitals. The Montreal cognitive assessment (MoCA) was used with a cutoff score of 26 to differentiate cognitive impairment. Univariable and multivariable logistic regression analyses were conducted to identify independent risk factors. A nomogram was then constructed based on the results of the multivariable logistic regression analysis. The patients had an average MoCA score of 23.99 ± 3.02. The multivariable logistic regression analysis revealed that age (OR: 1.096, 95% CI: 1.042–1.153, p < 0.001), education (OR: 0.065, 95% CI: 0.016–0.263, p < 0.001), depression severity (OR: 1.878, 95% CI: 1.021–3.456, p = 0.043), and sleep quality (OR: 2.454, 95% CI: 1.400–4.301, p = 0.002) were independent risk factors for cognitive impairment in patients with depressive disorder. The area under receiver operating characteristic (ROC) curves was 0.868 (95% CI: 0.807–0.929), indicating good discriminability of the model. The calibration curve of the model and the Hosmer–Lemeshow test (p = 0.571) demonstrated a well‐fitted model with high calibration. Age, education, depression severity, and sleep quality were found to be significant predictors of cognitive function. A nomogram model was developed to predict cognitive impairment in patients with depressive disorder, providing a solid foundation for clinical interventions.</description><identifier>ISSN: 0160-6891</identifier><identifier>ISSN: 1098-240X</identifier><identifier>EISSN: 1098-240X</identifier><identifier>DOI: 10.1002/nur.22364</identifier><identifier>PMID: 38149849</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Cognitive ability ; cognitive function ; Cognitive functioning ; Cognitive impairment ; Depressive personality disorders ; Hospitals ; independent risk factors ; major depressive disorder ; Mental depression ; nomogram ; Nomograms ; Regression analysis ; Risk factors ; Sleep</subject><ispartof>Research in nursing & health, 2024-06, Vol.47 (3), p.302-311</ispartof><rights>2023 Wiley Periodicals LLC.</rights><rights>2024 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3134-a3375fa33e1ce95bd5bbd1e65ff777b96d1e5a5cc9e53a5fd4ee23f22754799b3</cites><orcidid>0000-0001-7647-0138</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,30999</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38149849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jian, Ya‐Ling</creatorcontrib><creatorcontrib>Jia, Shoumei</creatorcontrib><creatorcontrib>Shi, Shenxun</creatorcontrib><creatorcontrib>Shi, Zhongying</creatorcontrib><creatorcontrib>Zhao, Ying</creatorcontrib><title>A nomogram to predict the risk of cognitive impairment in patients with depressive disorder</title><title>Research in nursing & health</title><addtitle>Res Nurs Health</addtitle><description>This study was to describe the cognitive function status in patients with depressive disorder and to construct a nomogram model to predict the risk factors of cognitive impairment in these patients. From October 2019 to February 2021, a total of 141 patients with depressive disorder completed the survey in two hospitals. The Montreal cognitive assessment (MoCA) was used with a cutoff score of 26 to differentiate cognitive impairment. Univariable and multivariable logistic regression analyses were conducted to identify independent risk factors. A nomogram was then constructed based on the results of the multivariable logistic regression analysis. The patients had an average MoCA score of 23.99 ± 3.02. The multivariable logistic regression analysis revealed that age (OR: 1.096, 95% CI: 1.042–1.153, p < 0.001), education (OR: 0.065, 95% CI: 0.016–0.263, p < 0.001), depression severity (OR: 1.878, 95% CI: 1.021–3.456, p = 0.043), and sleep quality (OR: 2.454, 95% CI: 1.400–4.301, p = 0.002) were independent risk factors for cognitive impairment in patients with depressive disorder. The area under receiver operating characteristic (ROC) curves was 0.868 (95% CI: 0.807–0.929), indicating good discriminability of the model. The calibration curve of the model and the Hosmer–Lemeshow test (p = 0.571) demonstrated a well‐fitted model with high calibration. Age, education, depression severity, and sleep quality were found to be significant predictors of cognitive function. A nomogram model was developed to predict cognitive impairment in patients with depressive disorder, providing a solid foundation for clinical interventions.</description><subject>Cognitive ability</subject><subject>cognitive function</subject><subject>Cognitive functioning</subject><subject>Cognitive impairment</subject><subject>Depressive personality disorders</subject><subject>Hospitals</subject><subject>independent risk factors</subject><subject>major depressive disorder</subject><subject>Mental depression</subject><subject>nomogram</subject><subject>Nomograms</subject><subject>Regression analysis</subject><subject>Risk factors</subject><subject>Sleep</subject><issn>0160-6891</issn><issn>1098-240X</issn><issn>1098-240X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><recordid>eNp10MtKxDAUBuAgijNeFr6ABNzook6u7WQpgzcYFMQBwUVI21Mn2jY1aRXf3oyjLgQ3ucB3fg4_QgeUnFJC2KQd_CljPBUbaEyJmiZMkIdNNCY0JUk6VXSEdkJ4JoRSyeg2GvEpFWoq1Bg9nuHWNe7Jmwb3DnceSlv0uF8C9ja8YFfhwj21trdvgG3TGesbaHtsW9yZ3sZnwO-2X-IS4mwIK1ba4HwJfg9tVaYOsP9976LFxfn97CqZ315ez87mScEpF4nhPJNVPIEWoGReyjwvKaSyqrIsy1UaP9LIolAguZFVKQAYrxjLpMiUyvkuOl7ndt69DhB63dhQQF2bFtwQNFMkzTLJuIr06A99doNv43aaE0EpEVzQqE7WqvAuBA-V7rxtjP_QlOhV4zo2rr8aj_bwO3HIGyh_5U_FEUzW4N3W8PF_kr5Z3K0jPwEJXYtN</recordid><startdate>202406</startdate><enddate>202406</enddate><creator>Jian, Ya‐Ling</creator><creator>Jia, Shoumei</creator><creator>Shi, Shenxun</creator><creator>Shi, Zhongying</creator><creator>Zhao, Ying</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7647-0138</orcidid></search><sort><creationdate>202406</creationdate><title>A nomogram to predict the risk of cognitive impairment in patients with depressive disorder</title><author>Jian, Ya‐Ling ; Jia, Shoumei ; Shi, Shenxun ; Shi, Zhongying ; Zhao, Ying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3134-a3375fa33e1ce95bd5bbd1e65ff777b96d1e5a5cc9e53a5fd4ee23f22754799b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Cognitive ability</topic><topic>cognitive function</topic><topic>Cognitive functioning</topic><topic>Cognitive impairment</topic><topic>Depressive personality disorders</topic><topic>Hospitals</topic><topic>independent risk factors</topic><topic>major depressive disorder</topic><topic>Mental depression</topic><topic>nomogram</topic><topic>Nomograms</topic><topic>Regression analysis</topic><topic>Risk factors</topic><topic>Sleep</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jian, Ya‐Ling</creatorcontrib><creatorcontrib>Jia, Shoumei</creatorcontrib><creatorcontrib>Shi, Shenxun</creatorcontrib><creatorcontrib>Shi, Zhongying</creatorcontrib><creatorcontrib>Zhao, Ying</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Research in nursing & health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jian, Ya‐Ling</au><au>Jia, Shoumei</au><au>Shi, Shenxun</au><au>Shi, Zhongying</au><au>Zhao, Ying</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A nomogram to predict the risk of cognitive impairment in patients with depressive disorder</atitle><jtitle>Research in nursing & health</jtitle><addtitle>Res Nurs Health</addtitle><date>2024-06</date><risdate>2024</risdate><volume>47</volume><issue>3</issue><spage>302</spage><epage>311</epage><pages>302-311</pages><issn>0160-6891</issn><issn>1098-240X</issn><eissn>1098-240X</eissn><abstract>This study was to describe the cognitive function status in patients with depressive disorder and to construct a nomogram model to predict the risk factors of cognitive impairment in these patients. From October 2019 to February 2021, a total of 141 patients with depressive disorder completed the survey in two hospitals. The Montreal cognitive assessment (MoCA) was used with a cutoff score of 26 to differentiate cognitive impairment. Univariable and multivariable logistic regression analyses were conducted to identify independent risk factors. A nomogram was then constructed based on the results of the multivariable logistic regression analysis. The patients had an average MoCA score of 23.99 ± 3.02. The multivariable logistic regression analysis revealed that age (OR: 1.096, 95% CI: 1.042–1.153, p < 0.001), education (OR: 0.065, 95% CI: 0.016–0.263, p < 0.001), depression severity (OR: 1.878, 95% CI: 1.021–3.456, p = 0.043), and sleep quality (OR: 2.454, 95% CI: 1.400–4.301, p = 0.002) were independent risk factors for cognitive impairment in patients with depressive disorder. The area under receiver operating characteristic (ROC) curves was 0.868 (95% CI: 0.807–0.929), indicating good discriminability of the model. The calibration curve of the model and the Hosmer–Lemeshow test (p = 0.571) demonstrated a well‐fitted model with high calibration. Age, education, depression severity, and sleep quality were found to be significant predictors of cognitive function. A nomogram model was developed to predict cognitive impairment in patients with depressive disorder, providing a solid foundation for clinical interventions.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>38149849</pmid><doi>10.1002/nur.22364</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-7647-0138</orcidid></addata></record> |
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subjects | Cognitive ability cognitive function Cognitive functioning Cognitive impairment Depressive personality disorders Hospitals independent risk factors major depressive disorder Mental depression nomogram Nomograms Regression analysis Risk factors Sleep |
title | A nomogram to predict the risk of cognitive impairment in patients with depressive disorder |
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