High homocysteine levels as potential indicators of subacute combined degeneration of the spinal cord

Homocysteine (Hcy) is widely recognized as a significant risk factor for cardiovascular and cerebrovascular diseases. However, our research has uncovered a novel perspective, suggesting that elevated levels of Hcy could serve as an indicator for neurological diseases. This article presents a unique...

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Bibliographic Details
Published in:The American journal of emergency medicine 2024-11, Vol.85, p.266.e5-266.e7
Main Authors: Feng, Tingting, Wang, Binru, Li, Fang, Li, Fengjiao, Wang, Shunxian, Zhou, Ruijiao, Wang, Lizhen, Lin, Hongyu, Ma, Ying
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Anemia
Ataxia
Cardiovascular diseases
Case report
Case reports
Cerebrovascular diseases
Cobalamin
Constipation
Copper
Degeneration
Electromyography
Emergency medical care
Folate
Hemoglobin
Homocysteine
Hyperhomocysteinemia
Magnetic resonance imaging
Metabolism
Neurological diseases
Older people
Patients
Proteins
R&D
Research & development
Risk factors
Spinal cord
Subacute combined degeneration of the spinal cord
Syphilis
Thyroid gland
Vascular diseases
Vitamin B
Vitamin B12
VitB12
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Description
Summary:Homocysteine (Hcy) is widely recognized as a significant risk factor for cardiovascular and cerebrovascular diseases. However, our research has uncovered a novel perspective, suggesting that elevated levels of Hcy could serve as an indicator for neurological diseases. This article presents a unique case of Subacute Combined Degeneration of the spinal cord(SCD), characterized by high homocysteine levels, yet normal vitamin B12 and imaging results. This discovery could facilitate early detection and ensure timely referral of patients to specialized departments for further treatment.
ISSN:0735-6757
1532-8171
1532-8171
DOI:10.1016/j.ajem.2023.11.065