Histologic scoring of liver biopsies for the prognosis of chronic liver disease at a tertiary care hospital in South India

The study aimed to evaluate the role of histologic scoring of liver biopsies using Ishak-modified histological activity index (HAI) and Laennec’s scoring system in predicting chronic liver disease (CLD) prognosis in South India. A retrospective analysis of liver biopsy samples was conducted at a ter...

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Bibliographic Details
Published in:Pathology, research and practice research and practice, 2024-01, Vol.253, p.155051-155051, Article 155051
Main Authors: Poorani, R., Ganesan, Nidhya, Neranchanaa, R., Chaitra, V., Kartikayan, R.K.
Format: Article
Language:English
Subjects:
Adult
Biopsy
Chronic liver disease
Female
Histology
Histopathology
Humans
Liver - pathology
Liver cirrhosis
Liver Cirrhosis - pathology
Liver Diseases - pathology
Male
Middle Aged
Prognosis
Retrospective Studies
Severity of Illness Index
Tertiary Care Centers
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Summary:The study aimed to evaluate the role of histologic scoring of liver biopsies using Ishak-modified histological activity index (HAI) and Laennec’s scoring system in predicting chronic liver disease (CLD) prognosis in South India. A retrospective analysis of liver biopsy samples was conducted at a tertiary care hospital. The samples were scored using the Ishak-modified HAI and Laennec’s scoring system for staging and grading CLD. Patient clinical data were retrieved and assessed using the Child-Pugh scoring system. Chi-squared test was used to test the association between categorical variables and the association with multiple categories was reported using Cramer’s V correlation coefficient. A p-value
ISSN:0344-0338
1618-0631
DOI:10.1016/j.prp.2023.155051