Comparison of Clinical and Genetic Characteristics Between Younger and Older Lung Cancer Patients

• Published in: Archivos de bronconeumología (English ed.) 2024-02, Vol.60 (2), p.88-94
• Main Authors: Candal-Pedreira, Cristina, Ruano-Ravina, Alberto, Calvo de Juan, Virginia, Cobo, Manuel, Trigo, José Manuel, Rodríguez-Abreu, Delvys, Estival, Anna, Carcereny, Enric, Cucurull, Marc, López Castro, Rafael, Medina, Andrea, García Campelo, Rosario, Cordeiro González, Patricia, Sánchez-Gastaldo, Amparo, Bosch-Barrera, Joaquim, Massutí, Bartomeu, Dómine, Manuel, Camps, Carlos, Ortega, Ana Laura, Sánchez-Hernández, Alfredo, Guirado Risueño, María, del Barco Morillo, Edel, Garrido Fernández, Alberto, Provencio, Mariano
• Format: Article
• Language: English
• Subjects: Anaplastic lymphoma kinase; Characteristics; Epidermal growth factor receptor; Genetic alterations; Lung cancer; Young patients
• ISSN: 0300-2896; 1579-2129
• DOI: 10.1016/j.arbres.2023.12.005

[Display omitted] The aim of this study was to analyze the clinical and genetic characteristics of young lung cancer cases, and to compare them with those of older cases. We used the Thoracic Tumors Registry (TTR) as a data source representative of lung cancer cases diagnosed in Spain, and included all cases registered until 9/01/2023 which had information on age at diagnosis or the data needed to calculate it. We performed a descriptive statistical analysis and fitted logistic regressions to analyze how different characteristics influenced being a younger lung cancer patient. A total of 26,336 subjects were included. Lung cancer cases