Challenges and pitfalls in classification of disproportionate mitral regurgitation

The concept of disproportionate mitral regurgitation (dispropMR) has been introduced to identify patients with functional mitral regurgitation (MR) who benefit from percutaneous treatment. We aimed to examine echocardiographic characteristics behind this entity. We retrospectively included 172 conse...

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Bibliographic Details
Published in:The international journal of cardiovascular imaging 2024-04, Vol.40 (4), p.757-767
Main Authors: Ambrožič, Jana, Rauber, Martin, Berlot, Boštjan, Škofic, Nataša, Toplišek, Janez, Bervar, Mojca, Cvijić, Marta
Format: Article
Language:English
Subjects:
Bias
Cardiac Imaging
Cardiology
Classification
Discordance
Echocardiography
Ejection fraction
Heart
Imaging
Mathematical analysis
Medicine
Medicine & Public Health
Orifices
Original Paper
Percutaneous treatment
Radiology
Regurgitation
Ultrasonic imaging
Velocity
Ventricle
Citations: Items that this one cites
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Description
Summary:The concept of disproportionate mitral regurgitation (dispropMR) has been introduced to identify patients with functional mitral regurgitation (MR) who benefit from percutaneous treatment. We aimed to examine echocardiographic characteristics behind this entity. We retrospectively included 172 consecutive patients with reduced left ventricular ejection fraction (LVEF), and more than mild MR referred to clinically indicated echocardiography. According to the proportionality ratio (effective regurgitant orifice area (EROA)/left ventricular end-diastolic volume (LVEDV)) patients were divided into dispropMR and proportionate MR (propMR) group. Potential factors which might affect proportionality definition were analyzed. 55 patients (32%) had dispropMR. Discrepant grading of MR severity was observed when using regurgitant volume (RegVol) by proximal isovelocity surface area (PISA) method or volumetric method, with significant discordance only in dispropMR (p 
ISSN:1875-8312
1569-5794
1875-8312
1573-0743
DOI:10.1007/s10554-023-03043-1