A Case Report of Kikuchi Fujimoto Disease as an Antecedent Illness of Systemic Lupus Erythematosus in a Male

Kikuchi Fujimoto disease (KFD) is a rare benign self-limiting condition described in young females characterized by lymphadenopathy and fever. It has been associated with several infective and autoimmune diseases, among which systemic lupus erythematosus (SLE) is relatively common. Kikuchi disease c...

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Bibliographic Details
Published in:Cureus 2023, Vol.15 (11), p.e49693-e49693
Main Authors: Munasinghe, K V P, Karunarathne, M A V M U, Sandamali, J A S, Munidasa, D
Format: Report
Language:English
Online Access:Get full text
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Summary:Kikuchi Fujimoto disease (KFD) is a rare benign self-limiting condition described in young females characterized by lymphadenopathy and fever. It has been associated with several infective and autoimmune diseases, among which systemic lupus erythematosus (SLE) is relatively common. Kikuchi disease could occur either as a proceeding illness or as a coexisting illness with SLE. The presence of necrotizing lymphadenitis is appreciated in the histological specimen to confirm the diagnosis. Anti-nuclear antibody (ANA) positivity implicates a possible correlation with SLE or recurrence of the pre-existing disease. This clinical presentation needs to be evaluated thoroughly to prevent misdiagnosis and inappropriate treatment. Although Kikuchi disease generally warrants supportive treatment, steroids and immune therapy play a role in treating this persistent and recurrent disease. Long-term surveillance is mandatory for the early detection of sinister pathologies.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.49693