Advances in magnetofection—magnetically guided nucleic acid delivery

Magnetofection is nucleic acid delivery to cells supported and site-specifically guided by the attractive forces of magnetic fields acting on nucleic acid shuttles (vectors) which are associated with magnetic nanoparticles. Recent progress with the method confirms its general applicability with smal...

Full description

Saved in:
Bibliographic Details
Published in:Journal of magnetism and magnetic materials 2005-05, Vol.293 (1), p.501-508
Main Authors: Schillinger, Ulrike, Brill, Thomas, Rudolph, Carsten, Huth, Stephanie, Gersting, Sören, Krötz, Florian, Hirschberger, Johannes, Bergemann, Christian, Plank, Christian
Format: Article
Language:English
Subjects:
Condensed matter: electronic structure, electrical, magnetic, and optical properties
Exact sciences and technology
Gene delivery
Gene therapy
Magnetic drug targeting
Magnetic properties and materials
Magnetofection
Physics
Small particles and nanoscale materials
Studies of specific magnetic materials
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Magnetofection is nucleic acid delivery to cells supported and site-specifically guided by the attractive forces of magnetic fields acting on nucleic acid shuttles (vectors) which are associated with magnetic nanoparticles. Recent progress with the method confirms its general applicability with small and large nucleic acids and viruses. The method's therapeutic application as well as mechanistic studies will be discussed.
ISSN:0304-8853
DOI:10.1016/j.jmmm.2005.01.032