Effects of a Nutraceutical Multicompound, with Probiotics, Hericium, PEA, and Undaria in Patients with Irritable Bowel Syndrome

• Published in: Journal of dietary supplements 2024-07, Vol.21 (4), p.1-461
• Main Authors: Romano, Antonio, Balestrini, Linda, Della Scala, Giulia, Chico, Lucia, Bertini, Alessio, Cangioli, Matilde, Ciapparelli, Federico, Ciardella, Enzo, Congestrí, Claudia, Dinelli, Valentina, Donati, Fabio, Ficini, Massimo, Giovanetti, Cecilia, Nannicini, Federico, Pasquali, Alessandro, Pieraccini, Andrea
• Format: Article
• Language: English
• ISSN: 1939-0211; 1939-022X; 1939-022X
• DOI: 10.1080/19390211.2023.2296106

Irritable bowel syndrome (IBS) is a functional gastrointestinal condition. Probiotics and other nutraceutical compounds can have specific indications in the context of IBS. A retrospective analysis was conducted on 123 IBS patients in order to evaluate the effects of an oral probiotic-based dietary supplement (Colicron, one cps/day for 4 wk) on stool consistency and pain intensity. Different time points were defined as follows: baseline (T0), 2 wk of treatment (T2), and 4 wk of treatment (T4). Stool consistency was assessed by using the Bristol Stool Scale. Pain intensity was evaluated by the Visual Analogue Scale (VAS). Patients who were initially categorized as normal retained regular bowel movements throughout the study. Both patients with constipation and diarrhea showed an improvement in the Bristol Stool Scale. The score increased from 1.5 ± 0.5 to 3.3 ± 0.7 (