Few-shot learning based oral cancer diagnosis using a dual feature extractor prototypical network

• Published in: Journal of biomedical informatics 2024-02, Vol.150, p.104584-104584, Article 104584
• Main Authors: Guo, Zijun, Ao, Sha, Ao, Bo
• Format: Article
• Language: English
• Subjects: Deep learning; Oral cancer; Pathology image; Prototypical network
• ISSN: 1532-0464; 1532-0480
• DOI: 10.1016/j.jbi.2024.104584

A large global health issue is cancer, wherein early diagnosis and treatment have proven to be life-saving. This holds true for oral cancer, thus emphasizing the significance of timely intervention. Deep learning techniques have gained traction in early cancer detection, exhibiting promising outcomes in accurate diagnosis. However, collecting a substantial amount of training data poses a challenge for deep learning models in cancer diagnosis. To address this limitation, this study proposes an oral cancer diagnosis approach based on a few-shot learning framework that circumvents the need for extensive training data. Specifically, a prototypical network is employed to construct a diagnostic model, wherein two feature extractors are utilized to extract prototypical features and query features respectively, departing from the conventional use of a single feature extraction function in prototypical networks. Moreover, a customized loss function is designed for the proposed method. Rigorous experimentation using a histopathological image dataset demonstrates the superior performance of our proposed approach over comparison methods. [Display omitted]