Long-term aspirin use in patients hospitalized with ischemic colitis

• Published in: Annals of gastroenterology 2024-01, Vol.37 (1), p.31-36
• Main Authors: Iqbal, Humzah, Haddadin, Rakahn, Zhang, Patrick, Haidary, Hasib, Prajapati, Devang
• Format: Article
• Language: English
• ISSN: 1108-7471
• DOI: 10.20524/aog.2024.0848

Ischemic colitis is a form of mesenteric ischemia that often presents in patients with vascular disease. Long-term aspirin use has been shown to improve the outcomes in patients with cardiovascular or cerebrovascular disease. However, the relationship between aspirin use and ischemic colitis is unclear. Patients with a diagnosis of ischemic colitis were identified using the 2020 Nationwide Inpatient Sample. Patients were stratified by long-term aspirin use at the time of hospitalization. Data were collected regarding mortality, bowel perforation, peritonitis, shock, blood transfusion, length of stay in days (LOS), hospital charges, age, sex, race, primary insurance, median income, hospital region, hospital size, and comorbidities. The relationship between aspirin use and outcomes was analyzed using multivariate regression analysis. A total of 67,685 patients were included. Aspirin users had a mean age of 72.8 years compared to 66.8 years for non-aspirin users. Long-term aspirin use was associated with a lower risk of in-hospital mortality (P