Volume-based 18F-FDG PET/CT predicts prognosis and outcome of active surveillance for intra-abdominal desmoid tumor

Purpose Desmoid tumor (DT) is a rare monoclonal, fibroblastic proliferation characterized by a variable and often unpredictable clinical course. Initial active surveillance is recommended by current guideline, and surgery is one of the main therapies for DT. Predicting the prognosis and outcome of a...

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Bibliographic Details
Published in:Abdominal imaging 2024-03, Vol.49 (3), p.958-963
Main Authors: Liu, Dao-Ning, Li, Cheng-Peng, Li, Hong-Wei, Wang, Hai-Yue, Tian, Xiu-Yun, Hao, Chun-Yi
Format: Article
Language:English
Subjects:
Abdomen
Fluorine isotopes
Gastroenterology
Glycolysis
Hepatology
Imaging
Medical prognosis
Medicine
Medicine & Public Health
Positron emission tomography
Practice
Prognosis
Radiology
Sensitivity
Surveillance
Tumors
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Summary:Purpose Desmoid tumor (DT) is a rare monoclonal, fibroblastic proliferation characterized by a variable and often unpredictable clinical course. Initial active surveillance is recommended by current guideline, and surgery is one of the main therapies for DT. Predicting the prognosis and outcome of active surveillance for intra-abdominal DT is pressing issue. Methods The study included eighteen patients with intra-abdominal DT. Metabolic tumor volume (MTV), total lesion glycolysis (TLG), and maximum standardized uptake value (SUVmax) were measured. We analyzed their relationship with the outcome of active surveillance, as well as clinical, prognostic, and pathological data. Results The MTV and TLG of recurrent DT were significantly higher than those of non-recurrent DT ( P  
ISSN:2366-0058
2366-004X
2366-0058
DOI:10.1007/s00261-023-04145-z