Nanostructuring of a porous alumina matrix for a biomolecular microarray

This paper describes a nanoporous substrate for applications in biomedical diagnostics. A photolithographic microstructuring technique for an ordered nanopore array fabrication is reported. The process uses a negative resist with hydrophobic properties increasing specificity to biomolecule linking....

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Bibliographic Details
Published in:Nanotechnology 2006-02, Vol.17 (3), p.795-798
Main Authors: Grasso, V, Lambertini, V, Ghisellini, P, Valerio, F, Stura, E, Perlo, P, Nicolini, C
Format: Article
Language:English
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Summary:This paper describes a nanoporous substrate for applications in biomedical diagnostics. A photolithographic microstructuring technique for an ordered nanopore array fabrication is reported. The process uses a negative resist with hydrophobic properties increasing specificity to biomolecule linking. Nanoporous alumina is formed by an anodic process and yields straight holes with high aspect ratio: its use as substrates for DNA-microarray or protein-chip application offers several advantages over conventional supports, making them very attractive to use as supports for biological sample microarray application.
ISSN:0957-4484
1361-6528
DOI:10.1088/0957-4484/17/3/030