Application of Advanced Imaging to Prostate Cancer Diagnosis and Management: A Narrative Review of Current Practice and Unanswered Questions

Major advances in prostate cancer diagnosis, staging, and management have occurred over the past decade, largely due to our improved understanding of the technical aspects and clinical applications of advanced imaging, specifically magnetic resonance imaging (MRI) and prostate-cancer-specific positr...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-01, Vol.13 (2), p.446
Main Authors: McKone, Elizabeth L, Sutton, Elsa A, Johnson, Geoffrey B, Phillips, Ryan M
Format: Article
Language:English
Subjects:
Biopsy
Cancer
Cancer therapies
Care and treatment
Clinical medicine
Clinical significance
Cohort analysis
Diagnosis
Magnetic resonance imaging
Medical diagnosis
Medical research
Medicine, Experimental
Methods
Patients
PET imaging
Prostate cancer
Surveillance
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Summary:Major advances in prostate cancer diagnosis, staging, and management have occurred over the past decade, largely due to our improved understanding of the technical aspects and clinical applications of advanced imaging, specifically magnetic resonance imaging (MRI) and prostate-cancer-specific positron emission tomography (PET). Herein, we review the established utility of these important and exciting technologies, as well as areas of controversy and uncertainty that remain important areas for future study. There is strong evidence supporting the utility of MRI in guiding initial biopsy and assessing local disease. There is debate, however, regarding how to best use the imaging modality in risk stratification, treatment planning, and assessment of biochemical failure. Prostate-cancer-specific PET is a relatively new technology that provides great value to the evaluation of newly diagnosed, treated, and recurrent prostate cancer. However, its ideal use in treatment decision making, staging, recurrence detection, and surveillance necessitates further research. Continued study of both imaging modalities will allow for an improved understanding of their best utilization in improving cancer care.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13020446