A novel separation and purification process for 1,3-propanediol

A novel isolation and purification method was developed for producing 1,3-propanediol with high purity and high yield from the mixture containing 1,3-propanediol, 1,2-propanediol, glycerol, and glucose. The developed method, which consisted of phase separation and chromatography, was found to be a s...

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Bibliographic Details
Published in:Process biochemistry (1991) 2006-03, Vol.41 (3), p.739-744
Main Authors: Cho, Mi-Hae, Joen, Sun Im, Pyo, Sang-Hyun, Mun, Sungyong, Kim, Jin-Hyun
Format: Article
Language:English
Subjects:
1,3-Propanediol
Chromatography
Phase separation
Purification
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Summary:A novel isolation and purification method was developed for producing 1,3-propanediol with high purity and high yield from the mixture containing 1,3-propanediol, 1,2-propanediol, glycerol, and glucose. The developed method, which consisted of phase separation and chromatography, was found to be a simple and efficient procedure for the isolation and purification of 1,3-propanediol from the other components in the mixture. The use of a phase separation process allows rapid separation of 1,3-propanediol from interfering compounds and dramatically reduces solvent usage compared to alternative methods. The overall purity and yield of 1,3-propanediol in this study were 98% and 82% in the purification process, respectively.
ISSN:1359-5113
1873-3298
DOI:10.1016/j.procbio.2005.11.013