Xylitol associated or not with fluoride: Is the action the same on de- and remineralization?

• Published in: Archives of oral biology 2024-03, Vol.159, p.105873-105873, Article 105873
• Main Authors: Carvalho, Thamyris Souza, Martini, Tatiana, Lima, Karen Pavan, Araújo, Tamara Teodoro, Feitosa, Chelsea Maria Vilas Boas, Marron, Luciana Rinaudi, Lavender, Stacey, Grizzo, Larissa Tercilia, Magalhães, Ana Carolina, Buzalaf, Marília Afonso Rabelo
• Format: Article
• Language: English
• ISSN: 0003-9969; 1879-1506
• DOI: 10.1016/j.archoralbio.2023.105873

This study evaluated the effect of xylitol combined or not with fluoride (F) on reduction of demineralization and increase of remineralization of shallow and deep artificial enamel lesions. Bovine enamel samples were allocated to the following solutions groups: no xylitol (negative control), 5% xylitol, 10% xylitol, 20% xylitol, 500 ppm F (as NaF), 5% xylitol+F, 10% xylitol+F or 20% xylitol+F (n = 12-15). For the demin study, a pH-cycling model (demineralization-6 h, pH 4.7/remineralization 18 h, pH 7.0) was employed for 7 days. Treatments were applied 2 × 1 min. In the remin study, specimens were pre-demineralized for 2, 5 or 10 days. Afterwards, a pH-cycling protocol was conducted (2 h demineralizing and 22 h remineralizing solution/day for 8 days) and the same treatments were done. The response variables were percentage surface hardness loss (%SHL) and transverse microradiography. Data were analyzed by RM ANOVA/Tukey or Kruskal-Wallis/Dunn (p