Site-directed research of magnetic nanoparticles in magnetic drug targeting

The targeting of ferrofluids composed of 20 nm magnetic particles was studied through simulation and animal experiment. The results showed that some magnetic particles were concentrated in the target area depending on the applied magnetic field. Through theoretical analysis, the retention of the mag...

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Bibliographic Details
Published in:Journal of magnetism and magnetic materials 2005-05, Vol.293 (1), p.514-519
Main Authors: Xu, Hua, Song, Tao, Bao, Xiuqi, Hu, Lili
Format: Article
Language:English
Subjects:
Atomic absorption spectrometer
Condensed matter: electronic structure, electrical, magnetic, and optical properties
Exact sciences and technology
Ferrofluids
Magnetic drug targeting
Magnetic force
Magnetic liquids
Magnetic properties and materials
MR imaging
NdFeB
Permanent magnet
Permanent magnets
Physics
Small particles and nanoscale materials
Sprague–Dawley rats
Studies of specific magnetic materials
Vibrating sample magnetometer
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Summary:The targeting of ferrofluids composed of 20 nm magnetic particles was studied through simulation and animal experiment. The results showed that some magnetic particles were concentrated in the target area depending on the applied magnetic field. Through theoretical analysis, the retention of the magnetic nanoparticles in a target area is due to large magnetic liquid beads formed by the magnetic field.
ISSN:0304-8853
DOI:10.1016/j.jmmm.2005.01.067