The associations of two novel inflammation indexes, systemic immune-inflammation index (SII) and system inflammation response index (SIRI), with periodontitis: evidence from NHANES 2009–2014

Objectives The research’s goal is to look for any potential relationships between the systemic immune-inflammation index (SII) and the system inflammation response index (SIRI), along with inflammation indicators and the likelihood of periodontitis. Methods Ten thousand two hundred eighty-two indivi...

Full description

Saved in:
Bibliographic Details
Published in:Clinical oral investigations 2024-02, Vol.28 (2), p.129-129, Article 129
Main Authors: Luo, Shiyi, Liu, Zefei, Jiao, Ruofeng, Li, Wei, Sun, Jiangling, Ma, Su, Song, Jukun, Chen, Zhu
Format: Article
Language:English
Subjects:
Biomarkers
Cross-Sectional Studies
Dentistry
Dentists
Gum disease
Humans
Inflammation
Medical diagnosis
Medicine
Nutrition Surveys
Periodontics
Periodontitis
Regression analysis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives The research’s goal is to look for any potential relationships between the systemic immune-inflammation index (SII) and the system inflammation response index (SIRI), along with inflammation indicators and the likelihood of periodontitis. Methods Ten thousand two hundred eighty-two individuals in sum were determined to be eligible for this cross-sectional study from the National Health and Nutrition Examination Survey (NHANES) between 2009 and 2014. Multiple logistic regression, generalized additive model, smooth curve fitting, subgroup analysis, and interaction tests were done for analyzing the association between periodontitis and SII, SIRI, and other inflammatory indicators. Results The analysis, adjusted for population weighting, revealed that individuals with moderate/severe periodontitis had SII levels of 545.46 (95% CI (529.10, 561.82), P  = 0.0044) and SIRI levels of 1.33 (95% CI (1.29, 1.37), P  
ISSN:1436-3771
1432-6981
1436-3771
DOI:10.1007/s00784-024-05529-1