Benefits and Risks of Medications Used in the Management of Hypotension: A Review

This comprehensive literature review addresses the scarcity and limited study of hypotension treatments compared to abundant antihypertensive drugs. Hypotension, categorized as absolute, relative, or orthostatic, has diverse causes. This review explores various treatments, including drugs affecting...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-01, Vol.16 (1), p.e51608-e51608
Main Authors: Skylynn, Thangwaritorn, Abel, Thomas, Christopher, Lee, Suliman, Ghafary, Dominic, Rivera, Joel, Varughese, Yu, Zeyu, Pemminati, Sudhakar
Format: Article
Language:English
Subjects:
Adrenergic receptors
Blood pressure
Caffeine
Cardiac arrhythmia
Dopamine
FDA approval
Heart rate
Hypertension
Mortality
Nausea
Nervous system
Orthostatic hypotension
Pharmacists
Urinary retention
Vomiting
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Summary:This comprehensive literature review addresses the scarcity and limited study of hypotension treatments compared to abundant antihypertensive drugs. Hypotension, categorized as absolute, relative, or orthostatic, has diverse causes. This review explores various treatments, including drugs affecting the sympathetic nervous system, such as midodrine, dihydroergotamine, and ergotamine, which have shown efficacy in managing hypotension. Dopamine agonists/antagonists and other drugs such as ephedrine, norepinephrine, and fludrocortisone are also discussed, each with distinct mechanisms and applications. Additionally, adjunctive agents such as non-steroidal anti-inflammatory agents, caffeine, and monoamine oxidase inhibitors are reviewed for their effects on blood pressure. This review underscores the importance of understanding the efficacy and safety profiles of hypotension treatments to guide healthcare professionals in optimal drug selection and management, emphasizing the need for further research and comparative studies for evidence-based guidelines.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.51608