Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term proposed to replace non-alcoholic fatty liver disease (NAFLD). We analyzed the ultrasonographic findings of MAFLD and NAFLD. We conducted a retrospective cross-sectional study of subjects aged ≥19 years who underwent a health...

Full description

Saved in:
Bibliographic Details
Published in:Clinical imaging 2024-04, Vol.108, p.110097-110097, Article 110097
Main Authors: Song, Byeong Geun, Kang, Tae Wook, Sinn, Dong Hyun, Kim, Yeun-Yoon, Min, Ji Hye, Hwang, Jeong Ah, Shin, Jaeseung
Format: Article
Language:English
Subjects:
Cirrhosis
Fatty liver
Ultrasonography
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c315t-104c83e98460896532f4f02ab32352c5849337932df30a8cb669037923595a033
container_end_page 110097
container_issue
container_start_page 110097
container_title Clinical imaging
container_volume 108
creator Song, Byeong Geun
Kang, Tae Wook
Sinn, Dong Hyun
Kim, Yeun-Yoon
Min, Ji Hye
Hwang, Jeong Ah
Shin, Jaeseung
description Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term proposed to replace non-alcoholic fatty liver disease (NAFLD). We analyzed the ultrasonographic findings of MAFLD and NAFLD. We conducted a retrospective cross-sectional study of subjects aged ≥19 years who underwent a health screening examination, including ultrasonography, (n = 17,066). Patients were separated into one of three groups; pure MAFLD (n = 5304), pure NAFLD (n = 579), and both NAFLD & MAFLD (n = 11,183). The outcomes were the degree of fatty liver disease and liver cirrhosis, defined by ultrasonography. In addition, the risk of ultrasonographic cirrhosis was assessed in the MAFLD group based on clinical characteristics. The pure NAFLD group had a lower risk of severe fatty liver disease than the both NAFLD & MAFLD groups (0.9 % vs. 4.4 %, p 
doi_str_mv 10.1016/j.clinimag.2024.110097
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2922449173</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0899707124000275</els_id><sourcerecordid>2922449173</sourcerecordid><originalsourceid>FETCH-LOGICAL-c315t-104c83e98460896532f4f02ab32352c5849337932df30a8cb669037923595a033</originalsourceid><addsrcrecordid>eNqFkUtvUzEQhS0EoqHwFyov2dzgx32ZFVXFS6rEhq4tZ2wnju61g8e3KH-pvxKnaVkhsbJ0fM6MznyEXHG25oz3H_ZrmEIMs9muBRPtmnPG1PCCrPg4yKZtlXpJVmxUqhnYwC_IG8Q9q0HVDq_JhRwlZ6MUK_JwN5VsMMW0zeawC0B9iDbELdLk6eyK2aSpqvaIfolQQoqNQUwQTHGWelPKkU7h3mVqAzqD7iO9ppDmg8mmVJ1iWeyR_g5lR-MpPEHaPY78R5aaaOljMTAThV2dAcXlgCUAviWvvJnQvXt6L8ndl88_b741tz--fr-5vm1A8q40nLUwSqfGtq_9-04K33omzEYK2QnoxlZJOSgprJfMjLDpe8WqUH9VZ5iUl-T9ee4hp1-Lw6LngOCmyUSXFtRCCVEPzIeTtT9bISfE7Lw-5MokHzVn-sRJ7_UzJ33ipM-cavDqaceymZ39G3sGUw2fzgZXm94HlzVCcBGcDdlB0TaF_-34AyATqpg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2922449173</pqid></control><display><type>article</type><title>Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Song, Byeong Geun ; Kang, Tae Wook ; Sinn, Dong Hyun ; Kim, Yeun-Yoon ; Min, Ji Hye ; Hwang, Jeong Ah ; Shin, Jaeseung</creator><creatorcontrib>Song, Byeong Geun ; Kang, Tae Wook ; Sinn, Dong Hyun ; Kim, Yeun-Yoon ; Min, Ji Hye ; Hwang, Jeong Ah ; Shin, Jaeseung</creatorcontrib><description><![CDATA[Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term proposed to replace non-alcoholic fatty liver disease (NAFLD). We analyzed the ultrasonographic findings of MAFLD and NAFLD. We conducted a retrospective cross-sectional study of subjects aged ≥19 years who underwent a health screening examination, including ultrasonography, (n = 17,066). Patients were separated into one of three groups; pure MAFLD (n = 5304), pure NAFLD (n = 579), and both NAFLD & MAFLD (n = 11,183). The outcomes were the degree of fatty liver disease and liver cirrhosis, defined by ultrasonography. In addition, the risk of ultrasonographic cirrhosis was assessed in the MAFLD group based on clinical characteristics. The pure NAFLD group had a lower risk of severe fatty liver disease than the both NAFLD & MAFLD groups (0.9 % vs. 4.4 %, p < 0.001). Cirrhosis was not diagnosed in the NAFLD group. Cirrhosis was more common in the pure MAFLD group than in the both NAFLD & MAFLD group (0.3 % vs. 0.0 %, p < 0.001). In the MAFLD group, multivariable analysis showed that diagnosis by hepatic steatosis index (Odds ratio [OR], 12.39; 95 % confidence interval [CI], 3.40–45.19; p < 0.001) or significant alcohol intake (OR, 9.58, 95 % CI, 1.93–47.61; p = 0.006) was independently associated with risk of liver cirrhosis on ultrasonography. Liver cirrhosis was more frequently identified on ultrasonography in patients with MAFLD than in NAFLD. MAFLD diagnosed using the hepatic steatosis index or significant alcohol intake is a risk factor for liver cirrhosis. •Cirrhosis was more frequently identified when we use MAFLD criteria compared to NAFLD.•Patients with both NAFLD and MAFLD had more severe fatty liver than those with pure NAFLD or MAFLD.•A high-risk group for cirrhosis can be identified using MAFLD criteria: hepatic steatosis index or significant alcohol intake.]]></description><identifier>ISSN: 0899-7071</identifier><identifier>EISSN: 1873-4499</identifier><identifier>DOI: 10.1016/j.clinimag.2024.110097</identifier><identifier>PMID: 38310832</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Cirrhosis ; Fatty liver ; Ultrasonography</subject><ispartof>Clinical imaging, 2024-04, Vol.108, p.110097-110097, Article 110097</ispartof><rights>2024 Elsevier Inc.</rights><rights>Copyright © 2024 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c315t-104c83e98460896532f4f02ab32352c5849337932df30a8cb669037923595a033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38310832$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Song, Byeong Geun</creatorcontrib><creatorcontrib>Kang, Tae Wook</creatorcontrib><creatorcontrib>Sinn, Dong Hyun</creatorcontrib><creatorcontrib>Kim, Yeun-Yoon</creatorcontrib><creatorcontrib>Min, Ji Hye</creatorcontrib><creatorcontrib>Hwang, Jeong Ah</creatorcontrib><creatorcontrib>Shin, Jaeseung</creatorcontrib><title>Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics</title><title>Clinical imaging</title><addtitle>Clin Imaging</addtitle><description><![CDATA[Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term proposed to replace non-alcoholic fatty liver disease (NAFLD). We analyzed the ultrasonographic findings of MAFLD and NAFLD. We conducted a retrospective cross-sectional study of subjects aged ≥19 years who underwent a health screening examination, including ultrasonography, (n = 17,066). Patients were separated into one of three groups; pure MAFLD (n = 5304), pure NAFLD (n = 579), and both NAFLD & MAFLD (n = 11,183). The outcomes were the degree of fatty liver disease and liver cirrhosis, defined by ultrasonography. In addition, the risk of ultrasonographic cirrhosis was assessed in the MAFLD group based on clinical characteristics. The pure NAFLD group had a lower risk of severe fatty liver disease than the both NAFLD & MAFLD groups (0.9 % vs. 4.4 %, p < 0.001). Cirrhosis was not diagnosed in the NAFLD group. Cirrhosis was more common in the pure MAFLD group than in the both NAFLD & MAFLD group (0.3 % vs. 0.0 %, p < 0.001). In the MAFLD group, multivariable analysis showed that diagnosis by hepatic steatosis index (Odds ratio [OR], 12.39; 95 % confidence interval [CI], 3.40–45.19; p < 0.001) or significant alcohol intake (OR, 9.58, 95 % CI, 1.93–47.61; p = 0.006) was independently associated with risk of liver cirrhosis on ultrasonography. Liver cirrhosis was more frequently identified on ultrasonography in patients with MAFLD than in NAFLD. MAFLD diagnosed using the hepatic steatosis index or significant alcohol intake is a risk factor for liver cirrhosis. •Cirrhosis was more frequently identified when we use MAFLD criteria compared to NAFLD.•Patients with both NAFLD and MAFLD had more severe fatty liver than those with pure NAFLD or MAFLD.•A high-risk group for cirrhosis can be identified using MAFLD criteria: hepatic steatosis index or significant alcohol intake.]]></description><subject>Cirrhosis</subject><subject>Fatty liver</subject><subject>Ultrasonography</subject><issn>0899-7071</issn><issn>1873-4499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFkUtvUzEQhS0EoqHwFyov2dzgx32ZFVXFS6rEhq4tZ2wnju61g8e3KH-pvxKnaVkhsbJ0fM6MznyEXHG25oz3H_ZrmEIMs9muBRPtmnPG1PCCrPg4yKZtlXpJVmxUqhnYwC_IG8Q9q0HVDq_JhRwlZ6MUK_JwN5VsMMW0zeawC0B9iDbELdLk6eyK2aSpqvaIfolQQoqNQUwQTHGWelPKkU7h3mVqAzqD7iO9ppDmg8mmVJ1iWeyR_g5lR-MpPEHaPY78R5aaaOljMTAThV2dAcXlgCUAviWvvJnQvXt6L8ndl88_b741tz--fr-5vm1A8q40nLUwSqfGtq_9-04K33omzEYK2QnoxlZJOSgprJfMjLDpe8WqUH9VZ5iUl-T9ee4hp1-Lw6LngOCmyUSXFtRCCVEPzIeTtT9bISfE7Lw-5MokHzVn-sRJ7_UzJ33ipM-cavDqaceymZ39G3sGUw2fzgZXm94HlzVCcBGcDdlB0TaF_-34AyATqpg</recordid><startdate>202404</startdate><enddate>202404</enddate><creator>Song, Byeong Geun</creator><creator>Kang, Tae Wook</creator><creator>Sinn, Dong Hyun</creator><creator>Kim, Yeun-Yoon</creator><creator>Min, Ji Hye</creator><creator>Hwang, Jeong Ah</creator><creator>Shin, Jaeseung</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202404</creationdate><title>Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics</title><author>Song, Byeong Geun ; Kang, Tae Wook ; Sinn, Dong Hyun ; Kim, Yeun-Yoon ; Min, Ji Hye ; Hwang, Jeong Ah ; Shin, Jaeseung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-104c83e98460896532f4f02ab32352c5849337932df30a8cb669037923595a033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Cirrhosis</topic><topic>Fatty liver</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Song, Byeong Geun</creatorcontrib><creatorcontrib>Kang, Tae Wook</creatorcontrib><creatorcontrib>Sinn, Dong Hyun</creatorcontrib><creatorcontrib>Kim, Yeun-Yoon</creatorcontrib><creatorcontrib>Min, Ji Hye</creatorcontrib><creatorcontrib>Hwang, Jeong Ah</creatorcontrib><creatorcontrib>Shin, Jaeseung</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Song, Byeong Geun</au><au>Kang, Tae Wook</au><au>Sinn, Dong Hyun</au><au>Kim, Yeun-Yoon</au><au>Min, Ji Hye</au><au>Hwang, Jeong Ah</au><au>Shin, Jaeseung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics</atitle><jtitle>Clinical imaging</jtitle><addtitle>Clin Imaging</addtitle><date>2024-04</date><risdate>2024</risdate><volume>108</volume><spage>110097</spage><epage>110097</epage><pages>110097-110097</pages><artnum>110097</artnum><issn>0899-7071</issn><eissn>1873-4499</eissn><abstract><![CDATA[Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term proposed to replace non-alcoholic fatty liver disease (NAFLD). We analyzed the ultrasonographic findings of MAFLD and NAFLD. We conducted a retrospective cross-sectional study of subjects aged ≥19 years who underwent a health screening examination, including ultrasonography, (n = 17,066). Patients were separated into one of three groups; pure MAFLD (n = 5304), pure NAFLD (n = 579), and both NAFLD & MAFLD (n = 11,183). The outcomes were the degree of fatty liver disease and liver cirrhosis, defined by ultrasonography. In addition, the risk of ultrasonographic cirrhosis was assessed in the MAFLD group based on clinical characteristics. The pure NAFLD group had a lower risk of severe fatty liver disease than the both NAFLD & MAFLD groups (0.9 % vs. 4.4 %, p < 0.001). Cirrhosis was not diagnosed in the NAFLD group. Cirrhosis was more common in the pure MAFLD group than in the both NAFLD & MAFLD group (0.3 % vs. 0.0 %, p < 0.001). In the MAFLD group, multivariable analysis showed that diagnosis by hepatic steatosis index (Odds ratio [OR], 12.39; 95 % confidence interval [CI], 3.40–45.19; p < 0.001) or significant alcohol intake (OR, 9.58, 95 % CI, 1.93–47.61; p = 0.006) was independently associated with risk of liver cirrhosis on ultrasonography. Liver cirrhosis was more frequently identified on ultrasonography in patients with MAFLD than in NAFLD. MAFLD diagnosed using the hepatic steatosis index or significant alcohol intake is a risk factor for liver cirrhosis. •Cirrhosis was more frequently identified when we use MAFLD criteria compared to NAFLD.•Patients with both NAFLD and MAFLD had more severe fatty liver than those with pure NAFLD or MAFLD.•A high-risk group for cirrhosis can be identified using MAFLD criteria: hepatic steatosis index or significant alcohol intake.]]></abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>38310832</pmid><doi>10.1016/j.clinimag.2024.110097</doi><tpages>1</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0899-7071
ispartof Clinical imaging, 2024-04, Vol.108, p.110097-110097, Article 110097
issn 0899-7071
1873-4499
language eng
recordid cdi_proquest_miscellaneous_2922449173
source ScienceDirect Freedom Collection 2022-2024
subjects Cirrhosis
Fatty liver
Ultrasonography
title Ultrasonographic findings of metabolic dysfunction-associated fatty liver disease: A comparative study with non-alcoholic fatty liver disease and clinical characteristics
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A19%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Ultrasonographic%20findings%20of%20metabolic%20dysfunction-associated%20fatty%20liver%20disease:%20A%20comparative%20study%20with%20non-alcoholic%20fatty%20liver%20disease%20and%20clinical%20characteristics&rft.jtitle=Clinical%20imaging&rft.au=Song,%20Byeong%20Geun&rft.date=2024-04&rft.volume=108&rft.spage=110097&rft.epage=110097&rft.pages=110097-110097&rft.artnum=110097&rft.issn=0899-7071&rft.eissn=1873-4499&rft_id=info:doi/10.1016/j.clinimag.2024.110097&rft_dat=%3Cproquest_cross%3E2922449173%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c315t-104c83e98460896532f4f02ab32352c5849337932df30a8cb669037923595a033%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2922449173&rft_id=info:pmid/38310832&rfr_iscdi=true