Transient ischemic attack and pregnancy, delivery and neonatal outcomes—An evaluation of a population database

• Published in: International journal of gynecology and obstetrics 2024-07, Vol.166 (1), p.412-418
• Main Authors: Amikam, Uri, Badeghiesh, Ahmad, Baghlaf, Haitham, Brown, Richard, Dahan, Michael H.
• Format: Article
• Language: English
• Subjects: Adult; Databases, Factual; Delivery, Obstetric - statistics & numerical data; Female; Humans; hypertensive disorders of pregnancy; Infant, Newborn; Ischemic Attack, Transient - epidemiology; maternal morbidity; perinatal outcomes; Pre-Eclampsia - epidemiology; Pregnancy; Pregnancy Complications, Cardiovascular - epidemiology; Pregnancy Outcome - epidemiology; Retrospective Studies; Risk Factors; transient ischemic attack; United States - epidemiology; venous thromboembolism; Young Adult
• ISSN: 0020-7292; 1879-3479; 1879-3479
• DOI: 10.1002/ijgo.15387

Objective Transient ischemic attack (TIA) is rare in women of reproductive age. We aimed to compare perinatal outcomes between women who suffered from a TIA to those who did not. Methods A retrospective population‐based cohort study utilizing the Healthcare Cost and Utilization Project, Nationwide Inpatient Sample (HCUP‐NIS). All women who delivered or had a maternal death in the US (2004–2014) were included in the study. Pregnancy, delivery, and neonatal outcomes were compared between women with an ICD‐9 diagnosis of a TIA to those without. Results Overall, 9 096 788 women met the inclusion criteria. Of these, 203 women (2.2/100000) had a TIA (either before or during pregnancy). Women with TIA, compared to those without, were more likely to be older than 35 years of age, white, in the highest income quartile, be insured by private insurance and suffer from obesity and chronic hypertension. Patients in the TIA group, compared to those without, had a higher rate of pregnancy‐induced hypertension (aOR 2.5, 95% CI: 1.55–4.05, P