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Targeted drug delivery to magnetic implants for therapeutic applications

A new method for locally targeted drug delivery is proposed that employs magnetic implants placed directly in the cardiovascular system to attract injected magnetic carriers. Theoretical simulations and experimental results support the assumption that using magnetic implants in combination with exte...

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Bibliographic Details
Published in:Journal of magnetism and magnetic materials 2005-05, Vol.293 (1), p.647-654
Main Authors: Yellen, Benjamin B., Forbes, Zachary G., Halverson, Derek S., Fridman, Gregory, Barbee, Kenneth A., Chorny, Michael, Levy, Robert, Friedman, Gary
Format: Article
Language:English
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Summary:A new method for locally targeted drug delivery is proposed that employs magnetic implants placed directly in the cardiovascular system to attract injected magnetic carriers. Theoretical simulations and experimental results support the assumption that using magnetic implants in combination with externally applied magnetic field will optimize the delivery of magnetic drug to selected sites within a subject.
ISSN:0304-8853
DOI:10.1016/j.jmmm.2005.01.083