Disparity Among African Americans in Transjugular Intrahepatic Portosystemic Shunt Procedure: A National Inpatient Sample Analysis from 2015 to 2020

• Published in: Digestive diseases and sciences 2024-03, Vol.69 (3), p.713-719
• Main Authors: Li, Renxi, Sarin, Shawn
• Format: Article
• Language: English
• Subjects: African Americans; Biochemistry; Black or African American; Gastroenterology; Generalized linear models; Hepatic Encephalopathy - epidemiology; Hepatic Encephalopathy - etiology; Hepatology; Humans; Hypertension, Portal - etiology; Inpatients; Liver cirrhosis; Liver Cirrhosis - complications; Liver Cirrhosis - diagnosis; Liver Cirrhosis - surgery; Medicine; Medicine & Public Health; Mortality; Oncology; Original Article; Portasystemic Shunt, Transjugular Intrahepatic - adverse effects; Retrospective Studies; Transplant Surgery; Treatment Outcome
• ISSN: 0163-2116; 1573-2568
• DOI: 10.1007/s10620-024-08273-4

Background Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure used to alleviate patients with chronic liver cirrhosis and portal hypertension. Racial disparities were present in TIPS where numerous studies suggested African American patients experience higher in-hospital mortality rates. However, the incidence of post-TIPS surgical complications, such as HE, has yet to be examined among African Americans. Therefore, this study aimed to provide a comprehensive examination of the disparities in TIPS procedures among African American patients. Methods The study compared African American and Caucasian patients who underwent TIPS procedures in the National Inpatient Sample (NIS) database from the last quarter of 2015–2020 after ICD-10 change. Preoperative variables, including demographics, comorbidities, primary payer status, and hospital characteristics, were examined and multivariable analysis was used to assess outcomes correcting preoperative variables with p