Oxygenation during general anesthesia in pediatric patients: A retrospective observational study

Protocols are used in intensive care and emergency settings to limit the use of oxygen. However, in pediatric anesthesiology, such protocols do not exist. This study aimed to investigate the administration of oxygen during pediatric general anesthesia and related these values to PaO2, SpO2 and SaO2....

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical anesthesia 2024-06, Vol.94, p.111406-111406, Article 111406
Main Authors: van Wijk, Jan J., Musaj, Albina, Hoeks, Sanne E., Reiss, Irwin K.M., Stolker, Robert Jan, Staals, Lonneke M.
Format: Article
Language:English
Subjects:
Anesthesia, General - adverse effects
Blood gas analysis
Blood Gas Analysis - methods
Catheters
Child
Children & youth
Clinical outcomes
Critical Care
General anesthesia
Humans
Hyperoxia
Intraoperative
Medical personnel
Monitoring
Observational studies
Oximetry - methods
Oxygen
Oxygen saturation
Oxygen therapy
Patients
Pediatrics
Perioperative care
Physiology
Ratios
Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Protocols are used in intensive care and emergency settings to limit the use of oxygen. However, in pediatric anesthesiology, such protocols do not exist. This study aimed to investigate the administration of oxygen during pediatric general anesthesia and related these values to PaO2, SpO2 and SaO2. Retrospective observational study. Tertiary pediatric academic hospital, from June 2017 to August 2020. Patients aged 0–18 years who underwent general anesthesia for a diagnostic or surgical procedure with tracheal intubation and an arterial catheter for regular blood withdrawal were included. Patients on cardiopulmonary bypass or those with missing data were excluded. Electronic charts were reviewed for patient characteristics, type of surgery, arterial blood gas analyses, and oxygenation management. No interventions were done. Primary outcome defined as FiO2, PaO2 and SpO2 values were interpreted using descriptive analyses, and the correlation between PaO2 and FiO2 was determined using the weighted Spearman correlation coefficient. Data of 493 cases were obtained. Of these, 267 were excluded for various reasons. Finally, 226 cases with a total of 645 samples were analyzed. The median FiO2 was 36% (IQR 31 to 43), with a range from 20% to 97%, and the median PaO2 was 23.6 kPa (IQR 18.6 to 28.1); 177 mmHg (IQR 140 to 211). The median SpO2 level was 99% (IQR 98 to 100%). The study showed a moderately positive association between PaO2 and FiO2 (r = 0.52, p 
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2024.111406