Diabetic Kidney Disease in Post-Kidney Transplant Patients

Post-transplant diabetes mellitus (PTDM) is a common occurrence in post-kidney transplantation and is associated with greater mortality, allograft failure, and increased risk of infections. The primary goal in the management of PTDM is to achieve glycemic control to minimize the risk of complication...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-01, Vol.13 (3), p.793
Main Authors: Pham, Ngoc-Yen T, Cruz, Diego, Madera-Marin, Luis, Ravender, Raja, Garcia, Pablo
Format: Article
Language:English
Subjects:
Belatacept
Care and treatment
Cell cycle
Complications and side effects
Development and progression
Diabetes
Diabetes therapy
Diabetic nephropathies
Diabetic nephropathy
Drug dosages
Drug therapy
Drug withdrawal
Glucose
Health aspects
Hyperglycemia
Immunotherapy
Insulin resistance
Kidney diseases
Kidney transplants
Kidneys
Liraglutide
Metabolism
Mortality
Mycophenolate sodium
Organ transplant recipients
Pathophysiology
Proteins
Quality of life
Risk factors
Signal transduction
Sitagliptin
Steroids
Transplantation
Transplantation of organs, tissues, etc
Type 2 diabetes
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Summary:Post-transplant diabetes mellitus (PTDM) is a common occurrence in post-kidney transplantation and is associated with greater mortality, allograft failure, and increased risk of infections. The primary goal in the management of PTDM is to achieve glycemic control to minimize the risk of complications while balancing the need for immunosuppression to maintain the health of the transplanted kidney. This review summarizes the effects of maintenance immunosuppression and therapeutic options among kidney transplant recipients. Patients with PTDM are at increased risk of diabetic kidney disease development; therefore, in this review, we focus on evidence supporting the use of novel antidiabetic agents and discuss their benefits and potential side effects in detail.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13030793