Prevalence of cannabis use disorder and perioperative outcomes in adult colectomy patients: A propensity score‐matched analysis

• Published in: World journal of surgery 2024-03, Vol.48 (3), p.701-712
• Main Authors: Lo, Brian D., Chen, Sophia Y., Stem, Miloslawa, Papanikolaou, Angelos, Gabre‐Kidan, Alodia, Safar, Bashar, Efron, Jonathan E., Atallah, Chady
• Format: Article
• Language: English
• Subjects: Adult; cannabis use disorder; colectomy; Colectomy - adverse effects; colorectal surgery; Humans; marijuana; Marijuana Abuse - epidemiology; morbidity; outcomes; Prevalence; Propensity Score; Retrospective Studies; United States - epidemiology
• ISSN: 0364-2313; 1432-2323
• DOI: 10.1002/wjs.12085

Background The decriminalization of cannabis across the United States has led to an increased number of patients reporting cannabis use prior to surgery. However, it is unknown whether preoperative cannabis use disorder (CUD) increases the risk of postoperative complications among adult colectomy patients. Methods Adult patients undergoing an elective colectomy were retrospectively analyzed from the National Inpatient Sample database (2004–2018). To control for potential confounders, patients with CUD, defined using ICD‐9/10 codes, were propensity score matched to patients without CUD in a 1:1 ratio. The association between preoperative CUD and composite morbidity, the primary outcome of interest, was assessed. Subgroup analyses were performed after stratification by age (≥50 years). Results Among 432,018 adult colectomy patients, 816 (0.19%) reported preoperative CUD. The prevalence of CUD increased nearly three‐fold during the study period from 0.8/1000 patients in 2004 to 2.0/1000 patients in 2018 (P‐trend