BRCA testing launched for people of Jewish ancestry in England

On Feb 1, 2024, the National Health Service (NHS) in England launched a national BRCA gene testing programme for all adults with Jewish ancestry (ie, at least one Jewish grandparent). The previous approach to BRCA testing in the UK was based on fulfilling family history criteria or standardised clin...

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Bibliographic Details
Published in:The lancet oncology 2024-03, Vol.25 (3), p.284-284
Main Author: Venkatesan, Priya
Format: Article
Language:English
Subjects:
Breast cancer
Cancer
Deoxyribonucleic acid
Disease prevention
DNA
Family medical history
Genealogy
Genes
Genetic screening
Genetic testing
Genomics
Medical diagnosis
Ovaries
Primary care
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Summary:On Feb 1, 2024, the National Health Service (NHS) in England launched a national BRCA gene testing programme for all adults with Jewish ancestry (ie, at least one Jewish grandparent). The previous approach to BRCA testing in the UK was based on fulfilling family history criteria or standardised clinical criteria (eg, after a cancer diagnosis), with complicated and time-intensive referral guidelines specifying which individuals would be eligible for genetic testing. Brittany Bychkovsky (Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, MA, USA) commented, “We rely on research efforts—some of which reach out to individuals in the Jewish community directly, and clinical referrals from primary care physicians.
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(24)00087-1