Operational characteristics of ultrasound in the diagnosis of Sjögren’s syndrome

• Published in: Radiología (English ed.) 2024-01, Vol.66 (1), p.13-22
• Main Authors: Guavita-Navarro, D., Ibáñez, C., Cajamarca-Barón, J., Avendaño Rodríguez, D.E., Torres-Castiblanco, J.L., Villamizar Barahona, A.B., Burbano Burbano, H.D., Escobar Trujillo, A., Polo, J.F., Rojas-Villarraga, A.
• Format: Article
• Language: English
• Subjects: Diagnostic imaging; Diagnóstico imagenológico; Female; Humans; Male; Middle Aged; ROC Curve; Salivary Glands - diagnostic imaging; Salivary Glands - pathology; Sensibilidad y especificidad; Sensitivity and Specificity; Sjogren's syndrome; Sjogren's Syndrome - diagnostic imaging; Sjogren's Syndrome - pathology; Síndrome de Sjögren; Ultrasonografía; Ultrasonography
• ISSN: 2173-5107; 2173-5107
• DOI: 10.1016/j.rxeng.2022.06.006

To determine the operational characteristics of salivary gland ultrasound (SGU) in the diagnosis of Sjögren’s syndrome (SS) in a population of colombian patients with dry symptoms. Study of diagnostic tests in patients with dry symptoms who consecutively attended the rheumatology consultation (2018–2020). Sociodemographic and clinical data were obtained through a survey, paraclinical and ophthalmological tests, minor salivary gland biopsy, unstimulated salivary flow and SGU (score 0–6 based on De Vita) were done. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values (Stata 15®) were calculated. The receiver operating characteristics (ROC) curve was developed. 102 patients were included (34 SS and 68 non-SS), mean age 55.69 (±11.93) years, 94% women. Positive ultrasound (score of 2 or more) was more frequent in the SS group, (70.6% vs. 22.1%, P