Giant adrenal myelolipoma in a young male double heterozygous for HbS and beta-thalassemia trait, clinically simulating retroperitoneal sarcoma

A 57-year-old male had abdominal pain and distension for 6-7 months with a palpable swelling in the right lumbar region. Contrast-enhanced computed tomography abdomen showed a large heterogeneous lesion with fat density measuring 22 cm ´ 16.5 cm in the right suprarenal region. Laparotomy was done wh...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2023-10, Vol.19 (7), p.2079-2081
Main Authors: Giri, Ranjana, Sahu, Saroj Ranjan, Parida, Sabyasachi, Sahu, Subrat Kumar
Format: Article
Language:English
Subjects:
Abdomen
Case reports
Comorbidity
Diagnosis
High performance liquid chromatography
Sarcoma
Thalassemia
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Summary:A 57-year-old male had abdominal pain and distension for 6-7 months with a palpable swelling in the right lumbar region. Contrast-enhanced computed tomography abdomen showed a large heterogeneous lesion with fat density measuring 22 cm ´ 16.5 cm in the right suprarenal region. Laparotomy was done which showed an encapsulated mass measuring 21 cm ´ 14 cm ´ 5 cm. Cut section revealed yellowish areas admixed with hemorrhage and large areas of necrosis. Microscopy revealed adrenal myelolipoma. The patient was found to have sickling positive. High-performance liquid chromatography showed double heterozygous for HbS and beta-thalassemia trait. The association of giant adrenal myelolipoma with double heterozygous for HbS and beta-thalassemia trait is rare, and as clinically it simulates retroperitoneal sarcoma, awareness of this rare entity is critical for its accurate diagnosis and proper management.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.jcrt_2127_21