Dysphagia as an Initial Presentation of Acute Myeloid Leukemia: A Rare Presentation of Myeloid Sarcoma

Myeloid sarcoma (MS) represents a unique clinical presentation of acute myeloid leukemia (AML). This report describes a case of MS in a 66-year-old man who presented with dysphagia, nausea, vomiting, anorexia, and fatigue. Generalized lymphadenopathy was noted on physical exam and confirmed by CT sc...

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Bibliographic Details
Published in:Cureus 2024, Vol.16 (1), p.e52624-e52624
Main Authors: Mohamed Salih, Rajaa, Olusoji, Rahman, Nwankwo, Chizoba, Osei, Noah, Kwentoh, Ifeoma P, Nwankwo, Obinna T
Format: Report
Language:English
Online Access:Get full text
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Summary:Myeloid sarcoma (MS) represents a unique clinical presentation of acute myeloid leukemia (AML). This report describes a case of MS in a 66-year-old man who presented with dysphagia, nausea, vomiting, anorexia, and fatigue. Generalized lymphadenopathy was noted on physical exam and confirmed by CT scans which also showed diffuse esophageal wall thickening. Axillary lymph node biopsy was positive for MS. Bone marrow biopsy confirmed AML with 88% blasts. The patient received induction chemotherapy with decitabine and venetoclax and was planned for four cycles of treatment over three months while monitoring the response.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.52624