Diagnostic and management strategies in cardiac sarcoidosis

Cardiac sarcoidosis (CS) is increasingly recognized in the context of with otherwise unexplained electrical or structural heart disease due to improved diagnostic tools and awareness. Therefore, clinicians require improved understanding of this rare but fatal disease to care for these patients. The...

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Bibliographic Details
Published in:International journal of cardiology 2024-05, Vol.403, p.131853-131853, Article 131853
Main Authors: Malhi, Jasmine K., Ibecheozor, Chukwuka, Chrispin, Jonathan, Gilotra, Nisha A.
Format: Article
Language:English
Subjects:
Arrhythmias
Cardiac sarcoidosis
Cardiomyopathy
Heart failure
Immunosuppression
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Summary:Cardiac sarcoidosis (CS) is increasingly recognized in the context of with otherwise unexplained electrical or structural heart disease due to improved diagnostic tools and awareness. Therefore, clinicians require improved understanding of this rare but fatal disease to care for these patients. The cardinal features of CS, include arrhythmias, atrio-ventricular conduction delay and cardiomyopathy. In addition to treatments tailored to these cardiac manifestations, immunosuppression plays a key role in active CS management. However, clinical trial and consensus guidelines are limited to guide the use of immunosuppression in these patients. This review aims to provide a practical overview to the current diagnostic challenges, treatment approach, and future opportunities in the field of CS. •Cardiac sarcoidosis (CS) should be considered in the right clinical context.•The cardinal manifestations of CS include conduction disease, arrhythmia or heart failure.•Immunosuppression is the cornerstone of treatment though with limited consensus data.•Heart failure and arrhythmia management are key components of multidisciplinary CS patient care.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2024.131853