FDG-Avid Periprosthetic Particle Disease Mimicking Osteosarcoma Recurrence

A 24-year-old man with a history of osteosarcoma presented with swelling in his right thigh for more than 1 year. 18 F-FDG PET/CT demonstrated increased FDG uptake in multiple juxtacortical masses around the prosthesis, which highly suggested the possibility of osteosarcoma recurrence. A biopsy was...

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Bibliographic Details
Published in:Clinical nuclear medicine 2024-04, Vol.49 (4), p.356-358
Main Authors: Dong, Ziqian, Guo, Ziyu, Guan, Meichao, Zhang, Yingjie, Xie, Peng
Format: Article
Language:English
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Summary:A 24-year-old man with a history of osteosarcoma presented with swelling in his right thigh for more than 1 year. 18 F-FDG PET/CT demonstrated increased FDG uptake in multiple juxtacortical masses around the prosthesis, which highly suggested the possibility of osteosarcoma recurrence. A biopsy was performed, and the pathology confirmed the diagnosis of particle disease. The current case indicates that particle disease should be considered when interpreting the PET/CT images with high FDG uptake around the prosthesis.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000005061