Linear IgA bullous dermatosis of childhood: Retrospective single-center cohort

Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disorder impacting children and adults. In this single-center retrospective chart review of pediatric patients with LABD at a large tertiary referral center, we report the unifying and unique clinical features of 10 pediatric patie...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric dermatology 2024-05, Vol.41 (3), p.461-464
Main Authors: Wang, Katherine L, Lehman, Julia S, Davis, Dawn M R
Format: Article
Language:English
Subjects:
Adolescent
Child
Child, Preschool
Children
Female
Humans
Immunoglobulin A
Infant
Linear IgA Bullous Dermatosis - diagnosis
Linear IgA Bullous Dermatosis - drug therapy
Linear IgA Bullous Dermatosis - pathology
Male
Morbidity
Patients
Pediatrics
Retrospective Studies
Skin diseases
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Linear IgA bullous dermatosis (LABD) is a rare autoimmune blistering disorder impacting children and adults. In this single-center retrospective chart review of pediatric patients with LABD at a large tertiary referral center, we report the unifying and unique clinical features of 10 pediatric patients. Patients typically presented with the "cluster of jewels" sign (n = 6; 60%), mucous membrane involvement (n = 5; 50%) and had a mean disease duration of 38 months; six patients (60%) required inpatient admission for management of their skin disease, including all five patients who had mucous membrane involvement. Our findings suggest that pediatric LABD may be a disease with high morbidity and may be associated with severe complications when mucous membranes are involved.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.15567