Automatic Tracking of Hyoid Bone Displacement and Rotation Relative to Cervical Vertebrae in Videofluoroscopic Swallow Studies Using Deep Learning

• Published in: Journal of digital imaging 2024-08, Vol.37 (4), p.1922-1932
• Main Authors: Li, Wuqi, Mao, Shitong, Mahoney, Amanda S, Coyle, James L, Sejdić, Ervin
• Format: Article
• Language: English
• Subjects: Annotations; Coordinates; Deep learning; Effectiveness; Error analysis; Hyoid bone; Kinematics; Localization; Pixels; Predictions; Rotation; Swallowing; Tracking; Vertebrae
• ISSN: 2948-2933; 0897-1889; 2948-2933; 1618-727X
• DOI: 10.1007/s10278-024-01039-4

The hyoid bone displacement and rotation are critical kinematic events of the swallowing process in the assessment of videofluoroscopic swallow studies (VFSS). However, the quantitative analysis of such events requires frame-by-frame manual annotation, which is labor-intensive and time-consuming. Our work aims to develop a method of automatically tracking hyoid bone displacement and rotation in VFSS. We proposed a full high-resolution network, a deep learning architecture, to detect the anterior and posterior of the hyoid bone to identify its location and rotation. Meanwhile, the anterior-inferior corners of the C2 and C4 vertebrae were detected simultaneously to automatically establish a new coordinate system and eliminate the effect of posture change. The proposed model was developed by 59,468 VFSS frames collected from 1488 swallowing samples, and it achieved an average landmark localization error of 2.38 pixels (around 0.5% of the image with 448 × 448 pixels) and an average angle prediction error of 0.065 radians in predicting C2–C4 and hyoid bone angles. In addition, the displacement of the hyoid bone center was automatically tracked on a frame-by-frame analysis, achieving an average mean absolute error of 2.22 pixels and 2.78 pixels in the x-axis and y-axis, respectively. The results of this study support the effectiveness and accuracy of the proposed method in detecting hyoid bone displacement and rotation. Our study provided an automatic method of analyzing hyoid bone kinematics during VFSS, which could contribute to early diagnosis and effective disease management.