Pineal gland germinoma with spinal drop metastases: A case report and review of literature

Germ cell tumor of the central nervous system (CNS) is an infrequent entity consisting of only 0.2%-1.7% of all primary CNS tumors. The pineal gland is the commonest location of CNS germinoma. Traditionally, radiotherapy alone has been used to treat localized pineal germinoma, which has delivered a...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2023-12, Vol.19 (Suppl 2), p.S904-S908
Main Authors: Nath, Jyotiman, Roy, Partha S, Sarma, Gautam, Sarma, Biswajit, Khanikar, Duncan
Format: Article
Language:English
Subjects:
Complications and side effects
Diagnosis
Drug therapy
Metastasis
Pineal parenchymal tumors
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Description
Summary:Germ cell tumor of the central nervous system (CNS) is an infrequent entity consisting of only 0.2%-1.7% of all primary CNS tumors. The pineal gland is the commonest location of CNS germinoma. Traditionally, radiotherapy alone has been used to treat localized pineal germinoma, which has delivered a very high cure rate. Spinal drop metastases from pineal germinoma can develop after a long time from diagnosis and primary treatment. Currently, craniospinal irradiation is the standard of care in metastatic pineal germinoma with spinal drop metastases along with systemic chemotherapy. Very few cases of pineal germinoma with spinal drop metastases have been published in the literature. We report a pineal gland germinoma case with spinal drop metastases in an 18-year-old boy and reviewed the published literature.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.jcrt_657_22