Weight Regain after Metabolic Surgery: Beyond the Surgical Failure

Patients undergoing metabolic surgery have factors ranging from anatomo-surgical, endocrine metabolic, eating patterns and physical activity, mental health and psychological factors. Some of the latter can explain the possible pathophysiological neuroendocrine, metabolic, and adaptive mechanisms tha...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-02, Vol.13 (4), p.1143
Main Authors: Salazar, Juan, Duran, Pablo, Garrido, Bermary, Parra, Heliana, Hernández, Marlon, Cano, Clímaco, Añez, Roberto, García-Pacheco, Henry, Cubillos, Gabriel, Vasquez, Neidalis, Chacin, Maricarmen, Bermúdez, Valmore
Format: Article
Language:English
Subjects:
Body mass index
Care and treatment
Fistula
Gastroesophageal reflux
Gastrointestinal surgery
Hernias
Metabolism
Morbidity
Mortality
Obesity
Ostomy
Overweight
Patient outcomes
Patients
Surgery
Surgical outcomes
Ulcers
Weight control
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Summary:Patients undergoing metabolic surgery have factors ranging from anatomo-surgical, endocrine metabolic, eating patterns and physical activity, mental health and psychological factors. Some of the latter can explain the possible pathophysiological neuroendocrine, metabolic, and adaptive mechanisms that cause the high prevalence of weight regain in postbariatric patients. Even metabolic surgery has proven to be effective in reducing excess weight in patients with obesity; some of them regain weight after this intervention. In this vein, several studies have been conducted to search factors and mechanisms involved in weight regain, to stablish strategies to manage this complication by combining metabolic surgery with either lifestyle changes, behavioral therapies, pharmacotherapy, endoscopic interventions, or finally, surgical revision. The aim of this revision is to describe certain aspects and mechanisms behind weight regain after metabolic surgery, along with preventive and therapeutic strategies for this complication.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13041143