Bariatric Surgery Outcomes in Patients with Inflammatory Bowel Disease in the United States: An Analysis of the Nationwide Readmissions Database

• Published in: Obesity surgery 2024-04, Vol.34 (4), p.1279-1285
• Main Authors: Wilson, Noah C., Dilsaver, Danielle B., Walters, Ryan W., Nandipati, Kalyana C.
• Format: Article
• Language: English
• Subjects: Bariatric Surgery - methods; Comorbidity; Gastrectomy - methods; Gastrointestinal surgery; Hospital costs; Hospitalization; Humans; Inflammatory bowel disease; Inflammatory Bowel Diseases - complications; Medicine; Medicine & Public Health; Obesity; Obesity - surgery; Obesity, Morbid - surgery; Original Contributions; Patient Readmission; Postoperative Complications - etiology; Retrospective Studies; Surgery; Treatment Outcome; United States; Weight control; Weight Loss
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-024-07111-w

Purpose Bariatric surgery has been reported to produce durable weight loss in the management of obesity; sleeve gastrectomy (SG) is the most common bariatric procedure. Obesity is a common comorbidity of inflammatory bowel disease (IBD), and the impact of IBD on short-term SG outcomes has not been widely reported. This study assessed whether IBD was associated with adverse post-SG outcomes. Materials and Methods Hospitalizations of patients undergoing SG in the United States were identified using the 2010–2020 Nationwide Readmissions Database (NRD) and stratified by IBD diagnosis. The SG cohort was propensity-matched based on age, biological sex, body mass index (BMI), comorbid diabetes, hypertension, depression, chronic obstructive pulmonary disease, and discharge in quarter four. Primary aims were to compare in-hospital mortality, post-operative complications, and all-cause 90-day readmission between patients with and without IBD. Secondary outcomes were length of stay (LOS) and total hospital cost. Results A total of 2030 hospitalizations were matched. The odds of complication were 48% higher for hospitalizations of patients with IBD (11.1% vs. 7.8%; aOR 1.48, aOR 95% CI 1.10–2.00, p  = .009). The most common complication was nausea (4.9% vs. 3.7%, p  = .187). No statistically significant difference was observed for all-cause 90-day readmissions, LOS, or hospital cost. Conclusion Hospitalizations of patients with IBD who underwent SG experienced significantly higher post-operative complication rates. However, the similar lengths of stay and readmission rates compared to propensity-matched SG hospitalizations without IBD suggest many complications were minor. SG remains a safe weight loss procedure for patients suffering from IBD and obesity. Graphical Abstract