Acute kidney injury in children undergoing cardiac surgery: predictive value of kidney arterial Doppler-based variables

Background Acute kidney injury (AKI) is a common condition in critically ill children and is associated with increased morbidity and mortality. This study aimed to assess the performance of point-of-care ultrasonography to predict AKI in children undergoing cardiac surgery. Methods In this prospecti...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2024-07, Vol.39 (7), p.2235-2243
Main Authors: De Souza, Fabiane M., De Carvalho, Aline V., Ferraz, Isabel S., Damiano, Ana P., Brandão, Marcelo B., Nogueira, Roberto J. N., De Souza, Tiago H.
Format: Article
Language:English
Subjects:
Acute Kidney Injury - diagnosis
Acute Kidney Injury - diagnostic imaging
Acute Kidney Injury - etiology
Cardiac Surgical Procedures - adverse effects
Child, Preschool
Children
Doppler effect
Female
Furosemide
Heart
Heart surgery
Humans
Infant
Kidney - blood supply
Kidney - diagnostic imaging
Kidney - physiopathology
Kidney diseases
Kidneys
Male
Medicine
Medicine & Public Health
Morbidity
Nephrology
Original Article
Pediatrics
Postoperative Complications - diagnosis
Postoperative Complications - diagnostic imaging
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Predictive Value of Tests
Prospective Studies
Pulsatile Flow
Renal Artery - diagnostic imaging
Ultrasonic imaging
Ultrasonography, Doppler - methods
Ultrasound
Urology
What’s new in AKI
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Acute kidney injury (AKI) is a common condition in critically ill children and is associated with increased morbidity and mortality. This study aimed to assess the performance of point-of-care ultrasonography to predict AKI in children undergoing cardiac surgery. Methods In this prospective study, consecutive children underwent kidney Doppler ultrasound examination within 24 h following cardiac surgery, and an experienced operator obtained both renal resistive index (RRI) and renal pulsatility index (RPI). AKI was defined by the Kidney Disease Improving Global Outcome (KDIGO) criteria. The primary outcome was the diagnosis of severe AKI (KDIGO stage 2 or 3) on day 3. Results A total of 58 patients were included. Median age and weight were 12.9 months (IQR 6.0–37.9) and 7.36 kg (IQR 5.19–11.40), respectively. On day 3, 13 patients were classified as having AKI, of which 11 were severe. RRI could effectively predict AKI (area under the ROC curve [AUC] 0.83, 95% CI 0.71–0.92; p  
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-024-06319-3