Laser spectroscopy and imaging of gallbladder stones, tissue and bile

Laser spectroscopic study of billary calculi and tissues is described. Fluorescence spectra of human gallbladder stones, bile and tissues were recorded with streak camera in the frequency and time domain. Potential of fluorescence as a diagnostic tool to discriminate between the intended target and...

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Bibliographic Details
Published in:Optics and lasers in engineering 2007, Vol.45 (1), p.191-197
Main Authors: Marafi, M., Kokaj, J., Bhatia, K.S., Makdisi, Y., Mathew, K.
Format: Article
Language:English
Subjects:
Biological and medical applications
Biological and medical sciences
Exact sciences and technology
Fluorescent spectroscopy
Fundamental and applied biological sciences. Psychology
Fundamental areas of phenomenology (including applications)
Gallbladder
General aspects, investigation technics, apparatus
Holographic interferometry
other holographic techniques
Holography
Instruments, apparatus, components and techniques common to several branches of physics and astronomy
Interferometers
Laser lithotripsy
Laser spectroscopy
Optical instruments, equipment and techniques
Optics
Physics
Shadowgraphy and interferometry
Tissues, organs and organisms biophysics
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Summary:Laser spectroscopic study of billary calculi and tissues is described. Fluorescence spectra of human gallbladder stones, bile and tissues were recorded with streak camera in the frequency and time domain. Potential of fluorescence as a diagnostic tool to discriminate between the intended target and the surrounding tissues and bile is evaluated. Initiation of fragmentation process is visualized by high-speed shadowgraphy, interferometry performed during the laser impact and generation of plasma causing growth and collapse of bubbles.
ISSN:0143-8166
1873-0302
DOI:10.1016/j.optlaseng.2006.03.014