Evaluating the effect of glycerol on increasing the safety and efficiency of hyperthermic laser lipolysis

This study aimed to investigate the effect of glycerol as an Optical Clearing Agent on the temperature profile of the skin during HyperThermic Laser Lipolysis using computer simulation. In this study, a three-layer model of the skin was used to simulate HyperThermic Laser Lipolysis. The Monte Carlo...

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Bibliographic Details
Published in:Lasers in medical science 2024-03, Vol.39 (1), p.84-84, Article 84
Main Authors: Vahidian, Afsane, Momayezan Marnani, Parvaneh, Mehdizadeh, Alireza, Rezaeian, Abbas, Ostovari, Mohsen
Format: Article
Language:English
Subjects:
Computer Simulation
Damage assessment
Dentistry
Epidermis
Finite element method
Glycerol
Impact damage
Lasers
Lipolysis
Medicine
Medicine & Public Health
Optical Devices
Optics
Original Article
Photonics
Photons
Quantum Optics
Radiation effects
Skin
Temperature profiles
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Summary:This study aimed to investigate the effect of glycerol as an Optical Clearing Agent on the temperature profile of the skin during HyperThermic Laser Lipolysis using computer simulation. In this study, a three-layer model of the skin was used to simulate HyperThermic Laser Lipolysis. The Monte Carlo MCML code was used to investigate the propagation of laser photons inside skin tissue. The energy absorbed from photons is used as a heat source to determine the increase in temperature and assess thermal damage in the layers of the skin. The finite element method in COMSOL software was used for calculation. The simulation of single-pulse radiation exposure with and without applying glycerol to the skin model was investigated to assess the impact of glycerol. Glycerol decreases the temperature and thermal damage to the epidermis layer while increasing the temperature of the fat layer. Moreover, the presence of glycerol increases the depth of fat cell destruction. Glycerol, as a supplement, significantly improves the efficacy of HyperThermic Laser Lipolysis.
ISSN:1435-604X
0268-8921
1435-604X
DOI:10.1007/s10103-024-04029-8