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Planning for the future of maternal immunization: Building on lessons learned from the COVID-19 pandemic
As the worldwide COVID-19 pandemic unfolded, the clinical and public health community raced to understand SARS-CoV-2 infection and develop life-saving vaccines. Pregnant persons were disproportionately impacted, experiencing more severe illness and adverse pregnancy outcomes. And yet, when COVID-19...
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Published in: | Vaccine 2024-09, Vol.42, p.125644, Article 125644 |
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creator | Meaney-Delman, Dana Carroll, Sarah Polen, Kara Jatlaoui, Tara C. Meyer, Sarah Oliver, Sara Gee, Julianne Shimabukuro, Tom Razzaghi, Hilda Riley, Laura Galang, Romeo R. Tong, Van Gilboa, Suzanne Ellington, Sascha Cohn, Amanda |
description | As the worldwide COVID-19 pandemic unfolded, the clinical and public health community raced to understand SARS-CoV-2 infection and develop life-saving vaccines. Pregnant persons were disproportionately impacted, experiencing more severe illness and adverse pregnancy outcomes. And yet, when COVID-19 vaccines became available in late 2020, safety and efficacy data were not available to inform their use during pregnancy because pregnant persons were excluded from pre-authorization clinical trials. Concerns about vaccine safety during pregnancy and misinformation linking vaccination and infertility circulated widely, creating a lack of vaccine confidence. Many pregnant people initially chose not to get vaccinated, and while vaccination rates rose after safety and effectiveness data became available, COVID-19 vaccine acceptance was suboptimal and varied across racial and ethnic distribution of the pregnant population. The COVID-19 pandemic experience provided valuable insights that can inform current and future approaches to maternal vaccination against. |
doi_str_mv | 10.1016/j.vaccine.2024.01.069 |
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Pregnant persons were disproportionately impacted, experiencing more severe illness and adverse pregnancy outcomes. And yet, when COVID-19 vaccines became available in late 2020, safety and efficacy data were not available to inform their use during pregnancy because pregnant persons were excluded from pre-authorization clinical trials. Concerns about vaccine safety during pregnancy and misinformation linking vaccination and infertility circulated widely, creating a lack of vaccine confidence. Many pregnant people initially chose not to get vaccinated, and while vaccination rates rose after safety and effectiveness data became available, COVID-19 vaccine acceptance was suboptimal and varied across racial and ethnic distribution of the pregnant population. The COVID-19 pandemic experience provided valuable insights that can inform current and future approaches to maternal vaccination against.</description><identifier>ISSN: 0264-410X</identifier><identifier>ISSN: 1873-2518</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2024.01.069</identifier><identifier>PMID: 38423818</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Clinical trials ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - prevention & control ; COVID-19 vaccines ; COVID-19 Vaccines - administration & dosage ; COVID-19 Vaccines - immunology ; Effectiveness ; Ethnic factors ; Female ; Humans ; Immunization ; Immunization - methods ; Infectious diseases ; Infertility ; Maternal immunization ; Pandemics ; Pandemics - prevention & control ; Pregnancy ; Pregnancy Complications, Infectious - prevention & control ; Public health ; Safety ; SARS-CoV-2 - immunology ; Severe acute respiratory syndrome coronavirus 2 ; Vaccination ; Vaccine ; Vaccines ; Viral diseases ; Womens health</subject><ispartof>Vaccine, 2024-09, Vol.42, p.125644, Article 125644</ispartof><rights>2024</rights><rights>Copyright © 2024. Published by Elsevier Ltd.</rights><rights>Copyright Elsevier Limited Sep 17, 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-976ecb04310e21c3d7e00c4a940c0e34b5408921d337b94a6bfe33f4a48d42b53</citedby><cites>FETCH-LOGICAL-c393t-976ecb04310e21c3d7e00c4a940c0e34b5408921d337b94a6bfe33f4a48d42b53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38423818$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Meaney-Delman, Dana</creatorcontrib><creatorcontrib>Carroll, Sarah</creatorcontrib><creatorcontrib>Polen, Kara</creatorcontrib><creatorcontrib>Jatlaoui, Tara C.</creatorcontrib><creatorcontrib>Meyer, Sarah</creatorcontrib><creatorcontrib>Oliver, Sara</creatorcontrib><creatorcontrib>Gee, Julianne</creatorcontrib><creatorcontrib>Shimabukuro, Tom</creatorcontrib><creatorcontrib>Razzaghi, Hilda</creatorcontrib><creatorcontrib>Riley, Laura</creatorcontrib><creatorcontrib>Galang, Romeo R.</creatorcontrib><creatorcontrib>Tong, Van</creatorcontrib><creatorcontrib>Gilboa, Suzanne</creatorcontrib><creatorcontrib>Ellington, Sascha</creatorcontrib><creatorcontrib>Cohn, Amanda</creatorcontrib><title>Planning for the future of maternal immunization: Building on lessons learned from the COVID-19 pandemic</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>As the worldwide COVID-19 pandemic unfolded, the clinical and public health community raced to understand SARS-CoV-2 infection and develop life-saving vaccines. Pregnant persons were disproportionately impacted, experiencing more severe illness and adverse pregnancy outcomes. And yet, when COVID-19 vaccines became available in late 2020, safety and efficacy data were not available to inform their use during pregnancy because pregnant persons were excluded from pre-authorization clinical trials. Concerns about vaccine safety during pregnancy and misinformation linking vaccination and infertility circulated widely, creating a lack of vaccine confidence. Many pregnant people initially chose not to get vaccinated, and while vaccination rates rose after safety and effectiveness data became available, COVID-19 vaccine acceptance was suboptimal and varied across racial and ethnic distribution of the pregnant population. The COVID-19 pandemic experience provided valuable insights that can inform current and future approaches to maternal vaccination against.</description><subject>Clinical trials</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>COVID-19 - prevention & control</subject><subject>COVID-19 vaccines</subject><subject>COVID-19 Vaccines - administration & dosage</subject><subject>COVID-19 Vaccines - immunology</subject><subject>Effectiveness</subject><subject>Ethnic factors</subject><subject>Female</subject><subject>Humans</subject><subject>Immunization</subject><subject>Immunization - methods</subject><subject>Infectious diseases</subject><subject>Infertility</subject><subject>Maternal immunization</subject><subject>Pandemics</subject><subject>Pandemics - prevention & control</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - prevention & control</subject><subject>Public 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subjects | Clinical trials COVID-19 COVID-19 - epidemiology COVID-19 - prevention & control COVID-19 vaccines COVID-19 Vaccines - administration & dosage COVID-19 Vaccines - immunology Effectiveness Ethnic factors Female Humans Immunization Immunization - methods Infectious diseases Infertility Maternal immunization Pandemics Pandemics - prevention & control Pregnancy Pregnancy Complications, Infectious - prevention & control Public health Safety SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Vaccination Vaccine Vaccines Viral diseases Womens health |
title | Planning for the future of maternal immunization: Building on lessons learned from the COVID-19 pandemic |
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