Antibiotic resistance and virulence genes profile of Non typhodial Salmonella species isolated from poultry enteritis in India

Salmonella species (spp) is the most important gastrointestinal pathogen present ubiquitously. Non typhoidal Salmonella (NTS) is commonly associated with gastroenteritis in humans. Layer birds once get infection with NTS, can become persistently infected with Salmonella Typhimurium and intermittentl...

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Bibliographic Details
Published in:Tropical animal health and production 2024-03, Vol.56 (2), p.91-91, Article 91
Main Authors: Sain, Arpita, Sharma, Deepak Kumar, Singathia, Rajesh, Gaurav, Abhishek, Patidar, Chaman, Suthar, PrabuRam, Rathore, Karishma, Juneja, Rohit
Format: Article
Language:English
Subjects:
Amikacin
Ampicillin
Antibiotic resistance
Antibiotics
Azithromycin
Bacteria
Biomedical and Life Sciences
Ceftriaxone
Ciprofloxacin
Cotrimoxazole
Drug resistance
Enteritis
Gastroenteritis
Genes
Gentamicin
Life Sciences
Multidrug resistance
Multidrug resistant organisms
Pathogenicity
Pathogens
Poultry
Public health
Regular Articles
Salmonella
Serology
Strains (organisms)
Veterinary Medicine/Veterinary Science
Virulence
Zoology
Zoonoses
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Summary:Salmonella species (spp) is the most important gastrointestinal pathogen present ubiquitously. Non typhoidal Salmonella (NTS) is commonly associated with gastroenteritis in humans. Layer birds once get infection with NTS, can become persistently infected with Salmonella Typhimurium and intermittently shed the bacteria. It results in a high risk of potential exposure of eggs to the bacteria. The current study was conducted to determine the serotype diversity, presence of virulence genes, antibiotic resistance pattern, and genes of NTS from poultry enteritis. Out of 151 intestinal swabs from poultry total 118 NTS were isolated, which were characterized serologically as S. Typhimurium (51 strains), S. Weltevreden (57 strains) and untypable (10 strains). Most effective antibiotics were amikacin, gentamycin and ceftriaxone (33.05%) followed by ampicillin, azithromycin and ciprofloxacin (16.69%), co-trimoxazole (13.55%), and tetracycline (6.78%). Multidrug resistance recorded in 17.70% (N = 21/118) strains. Antimicrobial-resistant genes  i.e.   blaTEM, blaSHV, blaCTX-M, tet(A), tet(B), tet(C), sul1, sul2, sul3. blaTEM  and  tet(A) were present in 95% (20/21). Eleven virulence genes  i.e. invA, hilA, sivH, tolC, agfA, lpfA, spaN, pagC, spiA, iroN  and  fliC  2 were present in all the 30 isolates. While,  sopE  was present in only 2 isolates, NTS strains with characteristics of pathogenicity and multidrug resistance from poultry enteritis were detected. Multidrug resistance showed the necessity of prudent use of antibiotics in the poultry industry.
ISSN:0049-4747
1573-7438
DOI:10.1007/s11250-024-03932-0